• Cortical Thickness Mapping to Identify Focal Osteoporosis in Patients with Hip Fracture

      Poole, Kenneth E.S.; Treece, Graham M.; Mayhew, Paul M.; Vaculí­k, Jan; Dungl, Pavel; Horák, Martin; Štӗpán, Jan J.; Gee, Andrew H.; Shi, Xing-Ming; Department of Pathology (2012-06-11)
      Background: Individuals with osteoporosis are predisposed to hip fracture during trips, stumbles or falls, but half of all hip fractures occur in those without generalised osteoporosis. By analysing ordinary clinical CT scans using a novel cortical thickness mapping technique, we discovered patches of markedly thinner bone at fracture-prone regions in the femurs of women with acute hip fracture compared with controls.