• Strategies and methods to study sex differences in cardiovascular structure and function: a guide for basic scientists

      Miller, Virginia M; Kaplan, Jay R; Schork, Nicholas J; Ouyang, Pamela; Berga, Sarah L; Wenger, Nanette K; Shaw, Leslee J; Webb, R. Clinton; Mallampalli, Monica; Steiner, Meir; et al. (2011-12-12)
      Background: Cardiovascular disease remains the primary cause of death worldwide. In the US, deaths due to cardiovascular disease for women exceed those of men. While cultural and psychosocial factors such as education, economic status, marital status and access to healthcare contribute to sex differences in adverse outcomes, physiological and molecular bases of differences between women and men that contribute to development of cardiovascular disease and response to therapy remain underexplored.