A gene-based approach for testing association of rare alleles
dc.contributor.author | Xu, Hongyan | |
dc.contributor.author | George, Varghese | |
dc.date.accessioned | 2012-10-26T20:30:43Z | en |
dc.date.available | 2012-10-26T20:30:43Z | en |
dc.date.issued | 2011-11-29 | en_US |
dc.identifier.citation | BMC Proc. 2011 Nov 29; 5(Suppl 9):S7 | en_US |
dc.identifier.issn | 1753-6561 | en_US |
dc.identifier.pmid | 22373566 | en_US |
dc.identifier.doi | 10.1186/1753-6561-5-S9-S7 | en_US |
dc.identifier.uri | http://hdl.handle.net/10675.2/781 | en |
dc.description.abstract | Rare genetic variants have been shown to be important to the susceptibility of common human diseases. Methods for detecting association of rare genetic variants are drawing much attention. In this report, we applied a gene-based approach to the 200 simulated data sets of unrelated individuals. The test can detect the association of some genes with multiple rare variants. | |
dc.rights | Copyright ©2011 Xu and George; licensee BioMed Central Ltd. | en_US |
dc.subject | Proceedings | en_US |
dc.title | A gene-based approach for testing association of rare alleles | en_US |
dc.type | Article | en_US |
dc.identifier.pmcid | PMC3287909 | en_US |
dc.contributor.corporatename | Department of Biostatistics and Epidemiology | en |
refterms.dateFOA | 2019-04-10T00:50:15Z | |
html.description.abstract | Rare genetic variants have been shown to be important to the susceptibility of common human diseases. Methods for detecting association of rare genetic variants are drawing much attention. In this report, we applied a gene-based approach to the 200 simulated data sets of unrelated individuals. The test can detect the association of some genes with multiple rare variants. |