• Login
    View Item 
    •   Home
    • Centers & Institutes
    • Georgia Prevention Center
    • Georgia Prevention Center: Faculty Research and Presentations
    • View Item
    •   Home
    • Centers & Institutes
    • Georgia Prevention Center
    • Georgia Prevention Center: Faculty Research and Presentations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of Scholarly CommonsCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    About

    AboutCreative CommonsAugusta University LibrariesUSG Copyright Policy

    Statistics

    Display statistics

    Differential Impact of Stress Reduction Programs upon Ambulatory Blood Pressure among African American Adolescents: Influences of Endothelin-1 Gene and Chronic Stress Exposure

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    IJHT2012-510291.pdf
    Size:
    673.7Kb
    Format:
    PDF
    Download
    Authors
    Gregoski, Mathew J.
    Barnes, Vernon A.
    Tingen, Martha S.
    Dong, Yanbin
    Zhu, Haidong
    Treiber, Frank A.
    Issue Date
    2011-11-24
    URI
    http://hdl.handle.net/10675.2/769
    
    Metadata
    Show full item record
    Abstract
    Stress-activated gene * environment interactions may contribute to individual variability in blood pressure reductions from behavioral interventions. We investigated effects of endothelin-1 (ET-1) LYS198ASN SNP and discriminatory stress exposure upon impact of 12-week behavioral interventions upon ambulatory BP (ABP) among 162 prehypertensive African American adolescents. Following genotyping, completion of questionnaire battery, and 24-hour ABP monitoring, participants were randomized to health education control (HEC), life skills training (LST), or breathing awareness meditation (BAM). Postintervention ABP was obtained. Significant three-way interactions on ABP changes indicated that among ET-1 SNP carriers, the only group to show reductions was BAM from low chronic stress environments. Among ET-1 SNP noncarriers, under low chronic stress exposure, all approaches worked, especially BAM. Among high stress exposure noncarriers, only BAM resulted in reductions. If these preliminary findings are replicated via ancillary analyses of archival databases and then via efficacy trials, selection of behavioral prescriptions for prehypertensives will be edging closer to being guided by individual's underlying genetic and environmental factors incorporating the healthcare model of personalized preventive medicine.
    Citation
    Int J Hypertens. 2012 Nov 24; 2012:510291
    ae974a485f413a2113503eed53cd6c53
    10.1155/2012/510291
    Scopus Count
    Collections
    Georgia Prevention Center: Faculty Research and Presentations

    entitlement

    Related articles

    • Impact of Stress Reduction Interventions on Hostility and Ambulatory Systolic Blood Pressure in African American Adolescents.
    • Authors: Wright LB, Gregoski MJ, Tingen MS, Barnes VA, Treiber FA
    • Issue date: 2011 May
    • Breathing awareness meditation and LifeSkills Training programs influence upon ambulatory blood pressure and sodium excretion among African American adolescents.
    • Authors: Gregoski MJ, Barnes VA, Tingen MS, Harshfield GA, Treiber FA
    • Issue date: 2011 Jan
    • Impact of breathing awareness meditation on ambulatory blood pressure and sodium handling in prehypertensive African American adolescents.
    • Authors: Barnes VA, Pendergrast RA, Harshfield GA, Treiber FA
    • Issue date: 2008 Winter
    • Influences of Family Environment and Meditation Efficacy on Hemodynamic Function among African American Adolescents.
    • Authors: Barnes VA, Gregoski MJ, Tingen MS, Treiber FA
    • Issue date: 2010 Jul
    • Meditation smartphone application effects on prehypertensive adults' blood pressure: Dose-response feasibility trial.
    • Authors: Adams ZW, Sieverdes JC, Brunner-Jackson B, Mueller M, Chandler J, Diaz V, Patel S, Sox LR, Wilder S, Treiber FA
    • Issue date: 2018 Sep
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.