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    Cardiometabolic Biomarkers in Young Black Girls: Relations to Body Fatness and Aerobic Fitness, and Effects of a Randomized Physical Activity Trial

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    Authors
    Gutin, Bernard
    Harris, Ryan A.
    Howe, Cheryl A.
    Johnson, Maribeth H.
    Zhu, Haidong
    Dong, Yanbin
    Issue Date
    2011-10-11
    URI
    http://hdl.handle.net/10675.2/759
    
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    Abstract
    There is little evidence from randomized trials showing that physical activity alone influences biomarker profiles in youths. This study tested two hypotheses: (i) that elevated body fatness and poor fitness would be associated with unfavorable levels of cardiometabolic biomarkers in 8- 12-y-old black girls (n = 242) and (ii) that a 10-mo PA intervention would have favorable effects on the fatness-related cardiometabolic biomarkers. At baseline, all fatness indices (i.e., percent body fat, visceral adipose tissue, BMI, and waist circumference) were significantly (P < 0.05) associated with unfavorable levels of insulin, glucose, systolic BP, diastolic BP, triglycerides, C-reactive protein (CRP), and fibrinogen. Aerobic fitness was significantly (P < 0.05) associated with favorable levels of insulin, CRP, fibrinogen, and HDL2. The PA intervention had significant and favorable effects on fitness, fatness, and two biomarkersâ resting heart rate and LDL cholesterol. More research is needed to clarify what types of interventions can enhance the cardiometabolic health of youths.
    Citation
    Int J Pediatr. 2011 Oct 11; 2011:219268
    ae974a485f413a2113503eed53cd6c53
    10.1155/2011/219268
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    Georgia Prevention Center: Faculty Research and Presentations

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