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dc.contributor.authorSayyid, Rashid K.
dc.contributor.authorHiffa, Anthony
dc.contributor.authorWoodruff, Phillip
dc.contributor.authorOberle, Michael D.
dc.contributor.authorLambert, Joshua H.
dc.contributor.authorTerris, Martha K.
dc.contributor.authorWallis, Christopher J.D.
dc.contributor.authorKlaassen, Zachary
dc.date.accessioned2023-10-11T16:31:49Z
dc.date.available2023-10-11T16:31:49Z
dc.date.issued2022
dc.identifier.citationSayyid, R. K., Hiffa, A., Woodruff, P., Oberle, M. D., Lambert, J. H., Terris, M. K., Wallis, C. J. D., & Klaassen, Z. (2022). Suspension of Oncology Randomized Clinical Trials during the COVID-19 Pandemic: A Cross-Sectional Evaluation of COVID-Related Suspensions. Cancer Investigation, 40(9), 743-749. https://doi.org/10.1080/07357907.2022.2104305en_US
dc.identifier.urihttp://hdl.handle.net/10675.2/624823
dc.description.abstractWe conducted a cross-sectional analysis of ClinicalTrials.gov-registered oncology randomized controlled trials between September 2019 and December 2021 to identify predictors of trial suspensions. The dataset included 1,183 oncology trials, of which 384 (32.5%) were suspended. COVID-19 accounted for 47 (12.2%) suspensions. Trials that were single center- or US-based had higher odds of COVID-19 (ORs: 3.85 and 2.48, 95% CIs: 1.60–11.50 and 1.28–4.93, respectively) or any-reason suspensions (ORs: 2.33 and 2.04, 95% CIs: 1.46–3.45 and 1.40–2.76, respectively). Phase two (OR 1.27), three (OR 6.45) and four trials (OR 11.5) had increased odds of COVID-19 suspensions, compared to phase one trials.en_US
dc.language.isoen_USen_US
dc.relation.url10.1080/07357907.2022.2104305en_US
dc.subjectCoronavirusen_US
dc.subjectoncologyen_US
dc.subjectpandemicen_US
dc.subjectrandomized controlled trialen_US
dc.subjectsuspensionsen_US
dc.titleSuspension of Oncology Randomized Clinical Trials during the COVID-19 Pandemic: A Cross-Sectional Evaluation of COVID-Related Suspensionsen_US
dc.typeArticleen_US
dc.typeJournal Volume/Issueen_US
dc.contributor.departmentAugusta Universityen_US
dc.identifier.journalCancer Investigationen_US
refterms.dateFOA2023-10-11T16:31:50Z


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