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dc.contributor.authorVarghese, Priyanka
dc.date.accessioned2023-08-03T18:36:45Z
dc.date.available2023-08-03T18:36:45Z
dc.date.issued2023-05
dc.identifier.urihttp://hdl.handle.net/10675.2/624728
dc.descriptionThe file you are attempting to access is restricted to Augusta University. Please login using your JagNet iD and password.en_US
dc.description.abstractThe human heart is one of the first organs to form and function during the development of a human embryo. Heart development is a highly complicated and tightly regulated process that culminates in the formation of the four-chamber heart. During the 6 to 7 weeks of human embryo development, the bottom of the heart tube forms the two atria, and the middle of the tube forms the two ventricles. The ventricular walls then begin to divide into all 4 chambers. Each chamber includes an entrance and exit for blood flow. Abnormal heart structure can impair heart contractility and can lead to Congestive Heart Disease (CHD). CHD is very prevalent in many children in where the heart does not pump a sufficient amount of blood into one’s body. According to the Center for Disease Control and Prevention (2008), “CHDs affect nearly 1% of?or about 40,000?births per year in the United States”. CHD can be caused by genetic or environmental cues that disrupt heart development (Lage et al., 2012). The mechanisms that lead to CHD are unfortunately not fully understood.
dc.language.isoen_USen_US
dc.publisherAugusta Universityen_US
dc.rightsCopyright protected. Unauthorized reproduction or use beyond the exceptions granted by the Fair Use clause of U.S. Copyright law may violate federal law.en_US
dc.rightsCopyright protected. Unauthorized reproduction or use beyond the exceptions granted by the Fair Use clause of U.S. Copyright law may violate federal law.en_US
dc.titleThe Role of Rbx1 in Cardiac Developmenten_US
dc.typeThesisen_US
dc.contributor.departmentBiologyen_US
dc.description.advisorHuabo Su
dc.description.committeeJennifer Cannon
dc.description.committeeCandis Bond
refterms.dateFOA2023-08-03T18:41:34Z
dc.description.embargo5/12/2028


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