• ATAD3A plays an oncogenic role in head and neck cancer

      Loveless, Jenni; Lang, Lewei; Jensen, Caleb; Teng, Yong; Dentistry (2020-02)
      With approximately 500,000 new cases diagnosed each year, head and neck squamous cell carcinomas (HNSCC) remain one of the leading causes of cancer related deaths. Thus, there is great interest to identify novel therapeutic targets against HNSCC. In this project, we aim to gain a deeper appreciation of ATAD3A, the ATPase family AAA-domain containing protein3A, and its oncogenic role in HNSCC, as well as its potential as a target in future patient therapies.
    • The Clinical Aspects of Hypophosphatasia

      Baker, Abby; Simpson, Sage; Dental Hygiene (2020-02-13)
      OBJECTIVES: The purpose of this research is to educate the dental community on the effects of hypophosphatasia and the clinical manifestations it presents throughout the body and the oral cavity. METHODS: Hypophosphatasia is a rare inherited metabolic disorder that has a wide spectrum of disease presentation. Due to 300 types of ALP mutations, HPP has six different major forms: perinatal lethal, prenatal benign, infantile, childhood, adulthood, and odotohypophosphatasia. There are clinical signs presented throughout the body and the oral cavity. Premature exfoliation of primary dentition is the first clinical sign of hypophosphatasia in childhood. Two different studies were reviewed in order to compare similar symptoms of hypophosphatasia. RESULTS: In one case study there were 38 patients who reported similar symptoms. In 15 (39%) of the patients a history of fractures was present. In the same study 21 (55%) of the patients had recurring headaches, 4 (11%) of the patients experienced severe muscle weakness, 23 (61%) experienced recurring muscle pain, and 18 (47%) of the patients exhibited dental abnormalities. In another case study there were 9 patients that reported only dental signs of hypophosphatasia. Dental signs of HPP were shown in childhood in 8 (88%) of the patients. The premature loss of the primary dentition was shown in 7 (77%) of the patients, absent primary dentition in 1 (11%) of the patients, and delayed loss of primary teeth in 1 (11%) of the patients. CONCLUSIONS: Since hypophosphatasia is so rare, more studies are needed on the diagnosis, preventative methods, and treatments. The majority of HPP cases are diagnosed in adulthood which ensures the disorder could have been present during childhood and was overlooked. In order to diagnose the disorder promptly, there should be a thorough medical history and clinical signs must be evaluated. There is no cure or long term prognosis for the hypophosphatasia disorder.
    • Comparison of Bulk Fill composite and effectiveness of use by skill of practitioner.

      Patterson, Zachary; Rueggeberg, Fred; Hampton, Mary Cameron; Babb, Courtney; Arce, Roger; Urbanawiz, David; Dentistry (2020-02)
      To compare the brands Fill-Up and Sonic fill and the efficacy of the peripheral seal alone, as well as to the skill levels of novice and experienced practitioners.
    • A Dental Hygienist’s Role in Teledentistry

      Harmon, SaDora; Barajas, Tania; Dental Hygiene (2020-02)
      To educate Teledentistry as the new advancement in Dentistry. To elaborate on the Dental hygienist’s role in this new advancement.
    • Effect of Print Angulation on Surface Roughness of 3D-Printed Models

      Tolbert, Tyler; Brenes, Christian; Fantaski, Lincoln; Mettenburg, Don; Rueggeberg, Fred; Dentistry (2020-02)
      To measure/compare surface roughness of 3D-printed models made from the same STL file and fabricated using a variety of printer/resin types at different angulations.
    • The Effects of Erythritol on Dental Caries and Biofilm

      Carter, Shelby; Gailer, Hannah; Dental Hygiene (2020-02)
      This project sought to determine the effectiveness of erythritol on the prevention of dental caries and the reduction of dental biofilm.
    • The Effects Probiotics Have on The Oral Cavity

      Colbert, Antonisha; Hamm, Marissa; Dental Hygiene (2020-02)
      The purpose of this literature review is to explore the options of probiotics; to see if they could potentially inhibit the bad bacteria in the oral cavity.
    • Exposure Duration and Adhesive Cure Uniformity Under a Stainless Steel Bracket

      Patel, Mohit; Moquin, Caitlin; DeLeon, Eladio; Fortson, Weston; Mettenburg, Don; Rueggeberg, Fred; Pre-Dentistry (2020-02)
      Determine the effect of curing light exposure on adhesive paste hardness underneath a simulated stainless steel bracket.
    • The Future of Nano-Robots in Dentistry

      Cartledge, Brenna; Watson, Lindsey; Dental Hygiene (2020-02)
      Micro-robots are being used in the medical field for a variety of procedures, such as: drug delivery and precision therapeutics. This research is used to determine how micro-robots can be incorporated into dentistry.
    • How Effective is Velscope in Dentistry

      Abbkar, Fatima; Atchison, Sherina; Dental Hygiene (2020-02)
      Velscope is a handheld device that used to detect oral cancer as an adjunct with the intraoral physical examination, using autofluorescence. The purpose of this article is to evaluate the effectiveness of velscope in dentistry.
    • Human Saliva Contact Angles on Three Types of Denture Bases

      Baxter, John; Baxter, Mary; Brenes, Christian; Messer, Regina; Sheen, Goeff; Mettenburg, Don; Rueggeberg, Fred; Denistry (2020-02)
      Contemporary denture base resins are available as 3 types: conventional, heat-processed (CONV), 3D printed (PRINT), or 3D milled (MILLED). This project measured and compared surface contact angle of human saliva to each type denture base, either as-processed (AP) or polished (POL).
    • Invasion and Survival of Porphyromonas gingivalis in Human ARPE-19 Cells

      Yuan, Jessie; Swaminathan, Radhika; Cutler, Christopher; Arjunan, Pachiappan; Dentistry (2020-02)
      Age-related macular degeneration (AMD), a leading cause of irreversible vision loss in elderly is associated with several systemic conditions. Recent studies link Periodontal Disease (PD) to AMD. As we demonstrated previously, Porphyromonas gingivalis (Pg),a keystone oral-pathobiont that cause periodontitis, invades blood dendritic and gingival epithelial cells. However, there is no evidence that Pg invades retinal-pigment epithelial (RPE) cells. The primary objective of this study is to test whether Pg and its fimbrial-mutants invade human ARPE-19 cells after infection.
    • Optimizing Bond Strength of RMGI and Conventional Composite

      Villalobos, Vanessa; Pate, Charmi; Mettenburg, Don; Rueggeberg, Fred; Bloomquist, Ryan; Dentistry (2020-02)
      The “sandwich technique” of placing resin modified glass ionomer (RMGI) as the initial restorative material increment, followed by overlaying with light-cured composite, is a common clinical procedure. This project evaluated the effects of RMGI surface abrasion as well as dentin bonding agent components on the shear bond strength (SBS) of composite to RMGI.
    • Oral Manifestations of Crohn’s Disease and its effect on Dental Treatment

      Rudduck, Alannah; Watkins, Meghan; Dental Hygiene (2020-02)
      OBJECTIVES: The purpose of this literature review is to inform dental health care professionals about CD, the oral manifestations that may be present, and what treatment modifications may be necessary. METHODS: To research information for this paper, we using the keywords: “Crohn’s Disease,” “oral manifestations,” and “dental treatment.” We gathered the majority of our articles through PubMed and EBSCO. We narrowed our search criteria by eliminating sources that were greater than five years old and articles that were not peer-reviewed. RESULTS: In order to understand CD, there is a lot that still remains unknown, and much more research needs to be conducted. However, understanding the biomarker in recent studies is the most important factor in any health care profession. The use of interprofessional communication with the patient's nutritionist, physician, and dental health team to determine key factors that are associated with CD is currently very important for further research. It’s theorized that IL12 cytokine stimulation in Th1 mediated upregulation results of IFNY may be the primary factors of CD.4 The reasons why it is significant to be conscious of the signs and symptoms of CD is due to oral inflammation may precede the intestinal manifestations.4 In addition, it’s hypothesized that the inflammatory response of IBD raises the basal cytokine response that induces periodontal disease. Several studies have been looking into this relationship further. Additional studies have recognized that CD patients have higher attribution of periodontal disease, deeper pocket depth, and clinical attachment loss.4 CONCLUSIONS: Treatment alterations to make the patient more comfortable include scheduling short appointments in the morning and allowing time for frequent restroom breaks. Despite having minimal biofilm accumulation, these patients tend to have bleeding on probing, deep periodontal pockets, decay, missing teeth and/or extensive previous dental treatment.3 Thus, clinicians need to regularly monitor caries and periodontal risks to optimize CD patient’s oral health status. Knowledgeable clinicians that recognize CD signs and symptoms should refer patients to their physicians for further diagnosis. It’s believed the more that is learned about CD and other IBD, the more overlap we will see in the oral cavity. Limitations to our research include inconsistent data and misrepresented populations. To best benefit the population, research will need to continue in order to learn more about the disease, development and management, and ways to prevent CD and other IBD, as well as less aggressive treatment options.
    • Quality of Dental Care at Long-Term Care Facilities

      Crittenden, Erika; Lollie, Renisha; Dental Hygiene (2020-02)
      To examine whether direct access to dental hygienists in long-term care facilities would improve the oral health of the residents.
    • Resin Infiltration and Contouring for an Esthetic Makeover

      Alverson, Benjamin; Romero, Mario; Capehar, Kim; Dentistry (2020-02)
      Using bleaching, Icon resin infiltration technique and a putty matrix to improve esthetics and contour of anterior teeth with mild fluorosis.
    • Rheumatoid Arthritis and Periodontal Disease

      Wolfe, Hannah; Corley, Morgan; Dental Hygiene (2020-02)
      The objective is to find a correlation between Periodontal Disease and Rheumatoid Arthritis.
    • Scaling and Root Planing in Conjunction with Propolis Irrigation

      Kurowski, Ashley; Lowe, Elaine; Dental Hygiene (2020-02)
      Periodontal Disease is a highly prevalent oral disease in the United States and dental professionals are always seeking a new and improved method to help decrease or arrest the side effects. This research is looking to propose a new innate, financially feasible option for individuals battling periodontal disease.
    • Testing for Photoinitiator Type in Light-cured Orthodontic Bracket Adhesives

      Janzen, Jackie; Humes, Haylee; DeLeon, Eladio; Fortson, Weston; Mettenburg, Don; Rueggeberg, Fred; Dentistry (2020-02)
      To measure/compare flexural strength of light-cured orthodontic resins when exposed to different wavelength curing light sources.
    • Tip-to-Target Distance Effect on Irradiance Delivered by Dental Curing Lights

      Klein, Laura; Rueggeberg, Fred; Dentistry (2020-02)
      Dental light curing units (LCUs) are often evaluated using exitance irradiance values. These values do not predict irradiance levels observed at common working distances. This project categorized LCUs by the tip-to-target distances where exitance irradiance dropped by 50%.