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dc.contributor.authorBidram, Elham
dc.contributor.authorEsmaeili, Yasaman
dc.contributor.authorAmini, Abbas
dc.contributor.authorSartorius, Rossella
dc.contributor.authorTay, Franklin R.
dc.contributor.authorShariati, Laleh
dc.contributor.authorMakvandi, Pooyan
dc.date.accessioned2022-03-09T20:08:45Z
dc.date.available2022-03-09T20:08:45Z
dc.date.issued2021-05-12
dc.identifier.issn2373-9878
dc.identifier.doi10.1021/acsbiomaterials.1c00318
dc.identifier.urihttp://hdl.handle.net/10675.2/624249
dc.description.abstractHuman respiratory viral infections are the leading cause of morbidity and mortality around the world. Among the various respiratory viruses, coronaviruses (e.g., SARSCoV-2) have created the greatest challenge and most frightening health threat worldwide. Human coronaviruses typically infect the upper respiratory tract, causing illnesses that range from common cold-like symptoms to severe acute respiratory infections. Several promising vaccine formulations have become available since the beginning of 2021. Nevertheless, achievement of herd immunity is still far from being realized. Social distancing remains the only effective measure against SARS-CoV-2 infection. Nanobiotechnology enables the design of nanobiosensors. These nanomedical diagnostic devices have opened new vistas for early detection of viral infections. The present review outlines recent research on the effectiveness of nanoplatforms as diagnostic and antiviral tools against coronaviruses. The biological properties of coronavirus and infected host organs are discussed. The challenges and limitations encountered in combating SARS-CoV-2 are highlighted. Potential nanodevices such as nanosensors, nanobased vaccines, and smart nanomedicines are subsequently presented for combating current and future mutated versions of coronaviruses.en_US
dc.language.isoenen_US
dc.publisherAmerican Chemical Society (ACS)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectBiomedical Engineeringen_US
dc.subjectBiomaterialsen_US
dc.subject.meshCOVID-19, coronavirus, nanobiosensor, nanobased vaccine, SARS-CoV-2en_US
dc.titleNanobased Platforms for Diagnosis and Treatment of COVID-19: From Benchtop to Bedsideen_US
dc.typeArticleen_US
dc.identifier.eissn2373-9878
dc.contributor.departmentThe Graduate Schoolen_US
dc.identifier.journalACS Biomaterials Science and Engineeringen_US
dc.identifier.pii10.1021/acsbiomaterials.1c00318
dc.source.journaltitleACS Biomaterials Science & Engineering
dc.source.volume7
dc.source.issue6
dc.source.beginpage2150
dc.source.endpage2176
refterms.dateFOA2022-03-09T20:08:46Z


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