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dc.contributor.authorAbd El-Megid, Faika Youssef
dc.date.accessioned2020-11-25T19:21:46Z
dc.date.available2020-11-25T19:21:46Z
dc.date.issued1990-06
dc.identifier.urien
dc.identifier.urihttp://hdl.handle.net/10675.2/623705
dc.descriptionThe file you are attempting to access is currently restricted to Augusta University. Please log in with your NetID if off campus.
dc.description.abstractThe mechanisms of tooth extraction wound healing remain to be fully explored. Histological changes in wound healing at 5, 14 and 30 days after extraction and distribution of fibronectin and cytokeratins using immunocytochemical techniques were studied. Three mature mongrel dogs were used and thirty-six premolar extraction wounds were investigated. Five · day old sockets showed osteoblastic and os~eoclastic activity. Thirty day old sockets were filled with immature trabecular bone. Epithelial proliferation was noted in the five day wounds and was apparently complete by 14 days. Fibronectin was observed under the basement membrane of migrating epithelium at 5 days and in granulation tissues at 5 and 14 days. There was change in the cytokeratin expression of healing keratinocytes as indicated by PKK2 localization at basal and suprabasal epithelial cell layers in 5 and 30 day wounds. Our results indicate that fibronectin plays a major role in dog gingival healing. The change in cytokeratin expression might be related to the cells being in a hyperproliferative state as might be expected during wound healing.en_US
dc.language.isoen_USen_US
dc.publisherMedical College of Georgiaen_US
dc.rightsCopyright protected. Unauthorized reproduction or use beyond the exceptions granted by the Fair Use clause of U.S. Copyright law may violate federal law.en_US
dc.titleCytochemical and Histopathological Factors in Tooth Extraction Wound Healingen_US
dc.typeThesisen_US
dc.contributor.departmentDepartment of Oral Biologyen_US
dc.description.advisorMcKinney, Ralph V.
dc.description.committeeSingh, Baldev
dc.description.committeeRao, Raghunatha
dc.description.committeeSharawy, Mohamed
dc.description.committeeBarrett, Michael
dc.description.degreeMaster of Science in Oral Biologyen_US
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refterms.dateFOA2020-11-25T19:21:47Z


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