• Login
    View Item 
    •   Home
    • Theses and Dissertations
    • Theses and Dissertations
    • View Item
    •   Home
    • Theses and Dissertations
    • Theses and Dissertations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of Scholarly CommonsCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    About

    AboutCreative CommonsAugusta University LibrariesUSG Copyright Policy

    Statistics

    Display statistics

    The mechanobiology of cranial suture

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    Byron_Craig_PhD_2005.pdf
    Size:
    8.985Mb
    Format:
    PDF
    Download
    Authors
    Byron, Craig D.
    Issue Date
    2005-07
    URI

    http://hdl.handle.net/10675.2/622843
    
    Metadata
    Show full item record
    Abstract
    A central hypothesis that cranial suture growth and modeling vary with respect to the mechanical loading environment is tested in a mouse sagittal suture model using three Specific Aims. Experiments within these aims were designed to elucidate mechanisms of bone fon:llation and bone resorption at the cellular level and to determine how these / processes influence the morphology and perfo~an~e of cranial suture connective tissues. ·- It is argued that suture waveform complexity (measill;ed using fractal analysis) is ' \ generated by the positive coupling of o~te~~enesis ctlopg convex bone margins and bone . resorption along concave bone margins and that this turnover cycle is regulated in large part by mechanical forces acting on the suture bone-ligament interface. This suture formfunction relationship is believed to operate via mechanosensing mechanisms within skeletal connective tissues. Although mechanically-induced cell wounding appears to be involved in normal suture biology, it does not occur in the fashion predicted. Apoptosis is not directly implicated. Thus, it is predicted that bone resorption in cranial sutures does not localize according to regions of shear-induced cell death but rather to regions adjacent to osteoblastic activity. Tension rather than shear is most likely to be the driving force in this system.
    Affiliation
    School of Graduate Studies
    Collections
    Theses and Dissertations

    entitlement

     
    DSpace software (copyright © 2002 - 2021)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.