Recent Submissions

  • FLATFISH ASSEMBLAGE AND ABUNDANCE DIFFERENCES BETWEEN THE SAINT CATHERINES ISLAND AND SATILLA RIVER ESTUARIES

    Bickle, Abigail; Coleman, Alex; Brown, Jason; Thiruvaiyaru, Dharma; Sethuraman, Sankar; Department of Biological Sciences; Department of Mathematics; Reichmuth, Jessica; Saul, Bruce; Augusta University (2019-02-13)
    St. Catherines Island is a pristine uninhabited barrier island off of the Georgia coast, and is believed to have experienced less anthropogenic alteration when compared to mainland estuarine habitats. In contrast, the Satilla River estuary has been historically affected by human activity, especially during the construction of navigational "cuts" through the marsh in the early 1900s. These cuts were used to support economic gain no longer in the area. Because of the differences in human influence, we hypothesize the fish assemblages will be different. We compared abundance of various resident flatfish species captured when trawling and using gill nets in these two systems. As benthic species, flatfish may be especially affected by anthropogenic disturbances of the estuarine substrates. This study provides insight into the effects of human disturbances on benthic fish species populations and assemblages. We compared catch-per-unit effort for six flatfish species between data among several sites, seasonally, between 2015 and 2018. We also looked at environmental variables when comparing abundance. The data are reflective of differences that exist in resident flatfish populations, and this condition could be explained by anthropogenic activities.
  • SERUM-C TERMINAL CROSSLINKING TELOPEPTIDE (CTX) AS A PREDICTIVE BIOMARKER OF BISPHOSPHONATE-RELATED OSTEONECROSIS OF JAW (BRONJ): SYSTEMATIC REVIEW AND META-ANALYSIS

    Sun, Christina; Awad, Mohamed E; Jernigan, Joshua; College of Science and Mathematics; Department of Oral Biology; Dental College of Georgia; Elsalanty, Mohammed; Augusta University (2019-02-13)
    The aim of this systematic review was to evaluate the validity of using preoperative serum C-terminal crosslinking telopeptide (CTX) levels as predictive factor of increased risk of developing medication-related osteonecrosis of the jaw (MRONJ) in patients on bisphosphonate (BP) therapy who undergo invasive dental procedures. A search was conducted through PubMed, MEDLINE, and Web of Science, following PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions. Meta-analysis was conducted on the risk ratio. The methodological index for nonrandomized studies (MINORS) and Quality Appraisal of Reliability Studies (QAREL) checklist were used to assess quality. Eighteen clinical trials, involving 2301 patients were included. Most patients received Alendronate or Risedronate for an average of 62.14 months. The average serum CTX level in BP-treated patients before surgery was 217.67 pg/ml. Meta-analysis demonstrated that the cutoff in CTX level (150 pg/ml) was not predictive of BRONJ risk. The sensitivity of CTX value <150 pg/ml was 34.26% and the specificity was 77.08%. The use of CTX to diagnose BRONJ risk following dental procedures in bisphosphonate-treated patients is not justified. Further studies are needed to develop other reliable biomarkers.
  • EFFECTS OF CHRONIC ALOHOL AND GLUCOSE EXPOSURE ON VIABILITY OF ALVEOLAR MACROPHAGES

    Keller, Elizabeth; College of Science and Mathematics; College of Allied Health; Curry-McCoy, Tiana; Thomas, Amanda; Augusta University (2019-02-13)
    The adverse health risks associated with alcohol abuse and obesity are widely known by the general population. Although lesser known, studies have presented the lungs as secondary organs affected by such lifestyle factors. Healthy lungs are protected against infection and harmful airborne particles by macrophages, the working entities of the immune system which fight potential sources of infection. When these immune-responsive cells are compromised and unable to perform their functions, lung health may deteriorate. Therefore, a healthy pulmonary alveolar macrophage population is vital for adequate lung function. Chronic alcohol abuse and obesity have been shown to suppress alveolar macrophage function, thus lowering the lungs� first line of defense. The objective of this study is to determine the effects of exogenous ethanol and increased glucose concentration on macrophage size and viability via an�in vitro�study on NR8383 rat alveolar macrophages. The study measures macrophage viability under treatment conditions.
  • An Analysis of the Economy of Greece

    Mack, Michaela; Department of Mathematics (Augusta University, 2018-05)