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    • 20th Annual Phi Kappa Phi Student Research and Fine Arts Conference (2019)
    • 20th Annual PKP Student Research and Fine Arts Conference: Posters
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    DESIGN AND SYNTHESIS OF HYBRID CONJUGATES AS POTENTIAL ANTI-INFECTIVE AGENTS

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    Authors
    Littlefield, William E
    Wade, Margaret
    Makkanal, Tina
    Issue Date
    2019-02-13
    URI
    http://hdl.handle.net/10675.2/622138
    
    Metadata
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    Abstract
    Infectious diseases caused by pathogenic microorganisms are major challenges despite all the steps taken to control or cure. New drug development with high efficacy/selectivity for infectious diseases is a point of interest for many researchers. It has reported that tuberculosis is one of the ten major causes of death in the world. Multi-drug resistance (MDR) is another major concern in bacterial and fungal infections. The present study deals with the development of new conjugates of pyrazinoic acid and isoniazid linked via an amino acid. The synthesized conjugates show promising and interesting results against a variety of microbial strains, tuberculous and non-tuberculous mycobacteria. Molecular modeling studies were used for understanding and validation of the experimental data.
    Affiliation
    College of Science and Mathematics
    Department of Chemistry and Physics
    Description
    Presentation given at the 20th Annual Phi Kappa Phi Student Research and Fine Arts Conference
    Collections
    Materials Science Research Seminar Series
    Department of Chemistry and Physics: Student Research and Presentations
    20th Annual PKP Student Research and Fine Arts Conference: Posters

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