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dc.contributor.authorSood, Nitish
dc.contributor.authorMehra, Mehul
dc.date.accessioned2019-02-13T20:07:19Z
dc.date.available2019-02-13T20:07:19Z
dc.date.issued2/13/2019
dc.identifier.urihttp://hdl.handle.net/10675.2/622121
dc.descriptionPresentation given at the 20th Annual Phi Kappa Phi Student Research and Fine Arts Conferenceen
dc.description.abstractPhylogenetic tree construction can be a particularly challenging and time-intensive process. This study employs a novel computational approach to phylogenetic tree construction, using the Alu repeating element, a SINE. Repetitive elements including Short and Long Interspersed Nuclear Elements (SINEs/LINEs) have successfully been applied as accurate tools for phylogenetic analysis, as they are predominately unidirectional and homoplasy-free. However, previous analysis of phylogenetic relationships using these repeating elements has been limited to a small number of isolated repeats among relatively few organisms. As a highly repetitive sequence, the Alu element and its associated subfamilies can provide detailed analysis on evolutionary divergence among species in the Order Primates. This study identified shared sequences as Alu repeating elements that were conserved in both location and base-pair sequence between the primate genomes of interest. These shared sequences, derived from the Genome Library at the University of California San Diego, were analyzed to construct individual phylogenetic trees for each of the 49 Alu subfamilies. As this method solely requires the sequence analysis of available primate genomes, this serves as a cheaper and more time-efficient approach to phylogenetic tree construction for the Order Primates relative to biochemical and anatomical analysis.
dc.subjectAluen
dc.subjectPhylogenetic Treeen
dc.subjectBioinformaticsen
dc.titleSEQUENCE ANALYSIS OF ALU REPEATED ELEMENTS FOR PRIMATE PHYLOGENETIC TREE CONSTRUCTIONen
dc.typePoster Presentationen
dc.contributor.departmentDepartment of Biological Sciencesen
dc.contributor.departmentUniversity of California Berkeleyen
dc.contributor.affiliationAugusta Universityen
dc.contributor.sponsorBates, Christopheren
dc.contributor.sponsorMittal, Anaven
html.description.abstractPhylogenetic tree construction can be a particularly challenging and time-intensive process. This study employs a novel computational approach to phylogenetic tree construction, using the Alu repeating element, a SINE. Repetitive elements including Short and Long Interspersed Nuclear Elements (SINEs/LINEs) have successfully been applied as accurate tools for phylogenetic analysis, as they are predominately unidirectional and homoplasy-free. However, previous analysis of phylogenetic relationships using these repeating elements has been limited to a small number of isolated repeats among relatively few organisms. As a highly repetitive sequence, the Alu element and its associated subfamilies can provide detailed analysis on evolutionary divergence among species in the Order Primates. This study identified shared sequences as Alu repeating elements that were conserved in both location and base-pair sequence between the primate genomes of interest. These shared sequences, derived from the Genome Library at the University of California San Diego, were analyzed to construct individual phylogenetic trees for each of the 49 Alu subfamilies. As this method solely requires the sequence analysis of available primate genomes, this serves as a cheaper and more time-efficient approach to phylogenetic tree construction for the Order Primates relative to biochemical and anatomical analysis.


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