• Login
    View Item 
    •   Home
    • Conferences, Workshops, Lecture Series, and Symposiums
    • Phi Kappa Phi Student Research and Fine Arts Conference
    • 19th Annual Phi Kappa Phi Student Research and Fine Arts Conference (2018)
    • 19th Annual PKP Student Research and Fine Arts Conference: Posters
    • View Item
    •   Home
    • Conferences, Workshops, Lecture Series, and Symposiums
    • Phi Kappa Phi Student Research and Fine Arts Conference
    • 19th Annual Phi Kappa Phi Student Research and Fine Arts Conference (2018)
    • 19th Annual PKP Student Research and Fine Arts Conference: Posters
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of Scholarly CommonsCommunitiesTitleAuthorsIssue DateSubmit DateSubjectsThis CollectionTitleAuthorsIssue DateSubmit DateSubjects

    My Account

    LoginRegister

    About

    AboutCreative CommonsAugusta University LibrariesUSG Copyright Policy

    Statistics

    Display statistics

    Expression and Treatment of Pain-Related Depression of Fixed-Ratio and Progressive-Ratio Food-Maintained Behavior in Rats

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Baker, Frederick
    Frazier, Eric
    Marshall, Laura
    Sinclair, Sequoia
    Thakkar, Parth
    Issue Date
    2018-02-12
    URI
    http://hdl.handle.net/10675.2/621760
    
    Metadata
    Show full item record
    Abstract
    Increasingly, preclinical studies on the expression, mechanisms, and treatment of pain have been aimed at improving understanding of pain-related interference with behavior. Positively reinforced operant behaviors are sensitive to depression by physiologically relevant pain stimuli. Most studies using operant conditioning procedures to examine pain-related depression of behavior have used fixed-ratio schedules of reinforcement. The primary dependent variable in these studies is the rate of behavior. In contrast, the primary dependent variable in studies using progressive-ratio schedules of reinforcement is breakpoint. Breakpoint is defined as the total number of reinforcers earned, and is thought to be related to the subject's motivation to obtain the reinforcer. This study examined effects of pain and analgesic manipulations on behavior maintained under fixed-ratio and progressive-ratio schedules of behavior. Intraperitoneal injection of dilute lactic acid was more potent at depressing behavior under the fixed-ratio schedule compared to the progressive-ratio schedule. Ketoprofen was equipotent at blocking pain-related depression of behavior maintained under both schedules. These findings support the validity of operant procedures astools to examine candidateanalgesics for the treatment of pain-related depression of behavior. Moreover, the use of diverse schedules of reinforcement may yield important scientific information on the mechanisms underlying pain-related interference with behavior.
    Affiliation
    Department of Psychological Sciences
    Description
    Presentation given at the 19th Annual Phi Kappa Phi Student Research and Fine Arts Conference
    Collections
    19th Annual PKP Student Research and Fine Arts Conference: Posters

    entitlement

     
    DSpace software (copyright © 2002 - 2022)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.