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dc.contributor.authorGoulopoulou, Styliani
dc.contributor.authorFernhall, Bo
dc.contributor.authorKanaley, Jill A.
dc.date.accessioned2012-10-26T16:26:49Z
dc.date.available2012-10-26T16:26:49Z
dc.date.issued2010-08-29en_US
dc.identifier.citationInt J Pediatr. 2010 Aug 29; 2010:153780en_US
dc.identifier.issn1687-9759en_US
dc.identifier.pmid20862202en_US
dc.identifier.doi10.1155/2010/153780en_US
dc.identifier.urihttp://hdl.handle.net/10675.2/594
dc.description.abstractThe purpose of this study was to examine differences in pressor response and cardiovagal modulation during isometric handgrip exercise (IHG) between children and adults. Beat-to-beat heart rate (HR) and blood pressure were measured in 23 prepubertal children and 23 adults at baseline and during IHG. Cardiovagal modulation was quantified by analysis of HR variability. Mean arterial pressure responses to IHG were greater in adults compared to children (P < .05) whereas there were no group differences in HR responses (P > .05). Children had a greater reduction in cardiovagal modulation in response to IHG compared to adults (P < .05). Changes in mean arterial pressure during IHG were correlated with baseline cardiovagal modulation and force produced during isometric contraction (P < .05). In conclusion, differences in pressor reflex response between children and adults cannot be solely explained by differences in autonomic modulation and appear to be associated with factors contributing to the force produced during isometric contraction.
dc.rightsCopyright © 2010 Styliani Goulopoulou et al.en_US
dc.subjectResearch Articleen_US
dc.titleDevelopmental Changes in Hemodynamic Responses and Cardiovagal Modulation during Isometric Handgrip Exerciseen_US
dc.typeArticleen_US
dc.identifier.pmcidPMC2938431en_US
dc.contributor.corporatenameDepartment of Physiology
refterms.dateFOA2019-04-09T22:23:27Z
html.description.abstractThe purpose of this study was to examine differences in pressor response and cardiovagal modulation during isometric handgrip exercise (IHG) between children and adults. Beat-to-beat heart rate (HR) and blood pressure were measured in 23 prepubertal children and 23 adults at baseline and during IHG. Cardiovagal modulation was quantified by analysis of HR variability. Mean arterial pressure responses to IHG were greater in adults compared to children (P < .05) whereas there were no group differences in HR responses (P > .05). Children had a greater reduction in cardiovagal modulation in response to IHG compared to adults (P < .05). Changes in mean arterial pressure during IHG were correlated with baseline cardiovagal modulation and force produced during isometric contraction (P < .05). In conclusion, differences in pressor reflex response between children and adults cannot be solely explained by differences in autonomic modulation and appear to be associated with factors contributing to the force produced during isometric contraction.


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