Unnecessary Workup of Asymptomatic Neonates in the Era of Group B Streptococcus Prophylaxis
Authors
Buckler, BradBell, Jason
Sams, Ralph
Cagle, William
Bell, Sue Anne
Allen, Carla
Sutherland, Donald E.
Bhatia, Jatinder
Issue Date
2010-08-22
Metadata
Show full item recordAbstract
Asymptomatic term neonates born to mothers who are Group B Streptococcus (GBS) unknown or GBS positive but â inadequatelyâ treated prior to delivery do not require invasive laboratory evaluation. We conducted a retrospective cohort study of mother/baby dyads born from January 1, 2005 until September 30, 2007 at the Medical College of Georgia. Their current protocol is to obtain a Complete Blood Count with Differential (CBC with D), Blood Culture (BC), and C-reactive protein (CRP) after birth. Mother/baby dyads (n = 242) that met inclusion criteria were reviewed. Of these 242 babies 25 (10%) were started on antibiotics after the initial lab values were known. None of the blood cultures were positive and the CRP's were normal. The 2002 GBS guidelines call for laboratory evaluation of â at-riskâ neonates, but the workup of these babies is not only costly, it does not provide any advantage over old fashioned clinical observation for the evaluation and treatment of early onset GBS sepsis.Citation
Infect Dis Obstet Gynecol. 2010 Aug 22; 2010:369654ae974a485f413a2113503eed53cd6c53
10.1155/2010/369654
Scopus Count
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