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    Unnecessary Workup of Asymptomatic Neonates in the Era of Group B Streptococcus Prophylaxis

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    Authors
    Buckler, Brad
    Bell, Jason
    Sams, Ralph
    Cagle, William
    Bell, Sue Anne
    Allen, Carla
    Sutherland, Donald E.
    Bhatia, Jatinder
    Issue Date
    2010-08-22
    URI
    http://hdl.handle.net/10675.2/592
    
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    Abstract
    Asymptomatic term neonates born to mothers who are Group B Streptococcus (GBS) unknown or GBS positive but â inadequatelyâ treated prior to delivery do not require invasive laboratory evaluation. We conducted a retrospective cohort study of mother/baby dyads born from January 1, 2005 until September 30, 2007 at the Medical College of Georgia. Their current protocol is to obtain a Complete Blood Count with Differential (CBC with D), Blood Culture (BC), and C-reactive protein (CRP) after birth. Mother/baby dyads (n = 242) that met inclusion criteria were reviewed. Of these 242 babies 25 (10%) were started on antibiotics after the initial lab values were known. None of the blood cultures were positive and the CRP's were normal. The 2002 GBS guidelines call for laboratory evaluation of â at-riskâ neonates, but the workup of these babies is not only costly, it does not provide any advantage over old fashioned clinical observation for the evaluation and treatment of early onset GBS sepsis.
    Citation
    Infect Dis Obstet Gynecol. 2010 Aug 22; 2010:369654
    ae974a485f413a2113503eed53cd6c53
    10.1155/2010/369654
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    Department of Pediatrics: Faculty Research and Presentations

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