Dissecting the Roles of Reactive Oxygen Species in Cardiovascular Disease
dc.contributor.author | Wang, Yusi | |
dc.date.accessioned | 2015-10-15T16:33:10Z | en |
dc.date.available | 2015-10-15T16:33:10Z | en |
dc.date.issued | 2015-09 | en |
dc.identifier.uri | http://hdl.handle.net/10675.2/579777 | |
dc.description.abstract | Cardiovascular disease remains the leading cause of death in the USA. While much has been learned about the root causes, the underlying mechanisms remain incompletely understood. In particular, elevated levels of reactive oxygen species (ROS) have been observed in the vasculature of blood vessels from animal models and humans with hypertension, atherosclerosis and diabetes. The importance of ROS to cardiovascular disease and the mechanisms by which it alters the function of cells of the cardiovascular system are the goals of this dissertation. | |
dc.rights | Copyright protected. Unauthorized reproduction or use beyond the exceptions granted by the Fair Use clause of U.S. Copyright law may violate federal law. | en |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | superoxide | en |
dc.subject | Circadian Rhythm | en |
dc.subject | Reactive Oxygen Species (ROS) | en |
dc.subject | inflammation | en |
dc.title | Dissecting the Roles of Reactive Oxygen Species in Cardiovascular Disease | en |
dc.type | Dissertation | en |
dc.contributor.department | Vascular Biology Center | en |
dc.description.advisor | Fulton, Fulton | en |
dc.description.degree | Doctor of Philosophy with a Major in Vascular Biology | en |
dc.description.committee | Stepp, David; Venema, Richard; Rudic, Dan; Ramesh, Ganesan | en |
refterms.dateFOA | 2020-05-27T17:22:38Z | |
html.description.abstract | Cardiovascular disease remains the leading cause of death in the USA. While much has been learned about the root causes, the underlying mechanisms remain incompletely understood. In particular, elevated levels of reactive oxygen species (ROS) have been observed in the vasculature of blood vessels from animal models and humans with hypertension, atherosclerosis and diabetes. The importance of ROS to cardiovascular disease and the mechanisms by which it alters the function of cells of the cardiovascular system are the goals of this dissertation. |