Visual and Instructional Design Policies: Division Administration
Abstract10.02 Visual and Instructional Design Policies: Division Administration: The Division of Visual and Instructional Design is a self-supporting, cost-recovery entity vvithin Georgia Health Sciences University Office of Academic Affairs. Art and design produced by the unit is billed to the project director/department requesting the service. Charges are based on actual amounts of time required to complete the project. The division posts per-hour charges and vvill provide customers vvith cost estimates upon customer request, based on the artist's understanding of the scope of the work requested.
AffiliationGeorgia Health Sciences University
Description10.0 Visual and Instructional Design
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Design, Synthesis, and Anti-inflammatory Studies of NSAID Hybrid ConjugatesHonkanadavar, Hitesh; Department of Chemistry & Physics; Panda, Siva; Augusta University (2019-02-13)Non-steroidal anti-inflammatory drugs are one of the most common drugs administered worldwide as highly effective analgesic, antipyretic and anti-inflammatory agents. The drugs function by inhibiting the COX-2 enzyme system which leads to a decrease in inflammation; however, the drugs also inhibit the COX-1 enzyme system which is critical to normal renal function, gastric mucosal integrity, vascular homeostasis, and the autocrine response to circulating hormones which can lead to gastric ulcers and renal dysfunction. Hybrid conjugates of existing non-steroidal anti-inflammatory drugs (NSAIDs) have already been synthesized with Ibuprofen, Acetaminophen, and amino acids to increase potency and decrease toxicity. Computational chemistry studies of these compounds show that the free phenol moiety in acetaminophen plays a greater role in the inhibition of the COX 2 enzyme system than the amine moiety. The previous compounds utilized the phenol moiety to form the product. New hybrid conjugates of Ibuprofen and Acetaminophen via amino acid linkers have been synthesized, leaving the phenol moiety free. The compounds have been characterized by NMR and IR. Biological studies indicate that some of the synthesized compounds are showing improved potency when compared to Ibuprofen alone. Computational chemistry studies and molecular modeling will be used to support the�in-vivo�biological activity.
WILLIAMSON ETHER REACTION USING A SOLAR HEAT SOURCE DESIGNED FOR UNDERGRADUATE CHEMISTRY LABORATORIESHammond, Caroline; Wyman, Kailey; Blair, Gregory; Department of Chemistry and Physics; Agee, Brian; Augusta University (2019-02-13)Since the 1990�s, scientists have been attempting to make chemical synthesis procedures more environmentally friendly.� One area of environmental concern is the amount of electricity required to provide enough energy to complete an experiment. Recently proposed solar reflectors developed from satellite dishes have the ability to be incorporated into student laboratory procedures to eliminate electricity use while demonstrating green chemistry techniques at the same time. As a result, demand to incorporate more green chemistry techniques into student laboratories has increased. An effective means for minimizing the amount of electricity needed to drive chemical reactions to completion is proposed through the use of solar parabolic reflectors. A comparative study was conducted using an electrical and solar heat source on the Williamson Ether synthesis of 2-butoxynaphthalene. This reaction was chosen as the test reaction due to its widespread use among many undergraduate chemistry programs.