• Factors associated with turnover among nurses in Taiwan

      Yang, Ke-Ping Agnes; School of Nursing (1987-12)
      The purpose of this study wasta examine the factors r~lated to nurses' turnover in Taiwan, the Republiq, of Ghina. Abelson~s (1986) lntegrCllted Turnover a I I ' Process Model, which ass~mes a causal relationship between an-employee's perceptions of indi~idual, organizational, atld environmental factors and that individual's decision to leave thei·r job, provided the theoretical basis for this - r . . study. A retrospective, descriptive correlational study design was-employed. Two h~ndred ar:1d thirty-$eve~ n~wly hi..red registered nurses who nad vo'lu~tarily le~ ~heir last position within the lasj twelve months were chos~n from eight large teac~ing hospitals loqated in the f110St populated areas o.f Taiwan .. A two-part \ questionnaire, an adaptation of--McCios-key's 1974 toolJor studying nursing turnover in the U.~. was used to collect.the da~a. ,A paQel of ~ive experts judged ~ - \, -- ' ' ,.. _.... . tbe final questio,nnaire-to have .conter:1t and translation validity. The Cronbach's alpha reliability score for Part ll_~f the que$tionn~ire us~d in, thi~ st~,Jdy w~s 0.98. Organizational ·level factors considered' most impo~ant when seeking a job were cited by 84.4 percent of t~e respondents. All 45 reward or incentive items in Part II of the questionnaire would have influenced some of the respondents to remain in their last position. Correlation statistics, Pearson r, t-Test, and ·one-way AN OVA were employed to test the relationships between ten selected fndividual, organizational, o~ environmental level variables and . nurses' length of service. Finding$ indicate that there was a significant relationship between length of service and age, marital status, relationship behavior, salary, hospital bed size, and type of hospital (private or public). , - The desire for better financial compensation for their work, opportunities for career advancement through continuing and formal education, more professional recognition from their supervisors, pe·ers, and physicians for their contribution to patient care, and more autonomy in their clinical practice appear to be shared by nurses in the Republic of China and the United States. Recommended approaches based on these findings which will assist administrators in retention as well as recruitment of nurses are presented.
    • Factors in student attrition

      Laird, Lee; Nauright, Lynda; School of Nursing (1973-12)
    • Factors related to the practice of breast self-examination in registered nurses

      Harkness, Katherine T.; School of Nursing (Augusta University, 1991-11)
      The purpose of this study was to examine the relationship among Health Belief Model variables (perceived susceptibility,. seriousness, barriers, control, and health motivation), knowledge of breast cancer and breast self-examination (BSE), and sociodemographics to frequency of BSE practice in registered nurses. One hundred twenty two women completed a Demographic Data and Frequency of Breast Self-Examination Questionnaire, the Champion Health Belief Model Scale, and the Breast Cancer Knowledge Test. Pearson product moment correlation revealed perceived barriers to be inversely related to frequency of BSE practice (r = -.45, p <.001), whereas health motivation was positively related to frequency of BSE practice (r =.44, p <.001). Stepwise multiple regression using Health Belief Model variables found perceived barriers and health motivation contributed significantly to the variance in BSE frequency, accounting for 29% of the variance. When each scale was analyzed independently, barriers accounted for the largest , I portion of the variance (20.2X), and health motivation accounted for 8.5%. Relative to the findings, implications for nursing practice and future nursing research are addressed,
    • Factors That Promote or Inhabit Confrontation of Chemically Impaired Nurses by Nursing Administrators

      Harrell, Lisa G.; College of Nursing (Medical College of Georgia, 1989-06)
    • False coverage rate - adjusted smoothed bootstrap simultaneous confidence intervals for selected parameters

      Sun, Jing; Department of Biostatistics and Epidemiology (Augusta University, 2020-05)
      Many modern applications refer to a large number of populations with high dimensional parameters. Since there are so many parameters, researchers often draw inferences regarding the most significant parameters, which are called selected parameters. Benjamini and Yekutieli (2005) proposed the false coverage-statement rate (FCR) method for multiplicity correction when constructing confidence intervals for only selected parameters. FCR for the confidence interval method is parallel to the concept of the false discovery rate for multiple hypothesis testing. In practice, we typically construct FCR-adjusted approximate confidence intervals for selected parameters either using the bootstrap method or the normal approximation method. However, these approximated confidence intervals show higher FCR for small and moderate sample sizes. Therefore, we suggest a novel procedure to construct simultaneous confidence intervals for the selected parameters by using a smoothed bootstrap procedure. We consider a smoothed bootstrap procedure using a kernel density estimator. A pertinent problem associated with the smoothed bootstrap approach is how to choose the unknown bandwidth in some optimal sense. We derive an optimal choice for the bandwidth and the resulting smoothed bootstrap confidence intervals asymptotically to give better control of the FCR than its competitors. We further show that the suggested smoothed bootstrap simultaneous confidence intervals are FCR-consistent if the dimension of data grows no faster than N^3/2. Finite sample performances of our method are illustrated based on empirical studies. Through these empirical studies, it is shown that the proposed method can be successfully applied in practice.
    • Fast Axonal Transport and Distal Protein Accumulation in Acrylamide Neuropathy

      Clarke, Charlotte Harris; School of Graduate Studies (Medical College of Georgia, 1995-06-01)
    • Feasibility of immunogold visualization of nuclear antigens by scanning electron microscopy

      Smith, Mary Leverett; Department of Cell and Molecular Biology (1987-09)
    • Fecal Streptococci Determinations In Water From a Small Urban Lake and Tributary

      Bruker, Eugene; Department of Cell and Molecular Biology (1962-06)
    • Female Teens Step It Up with the Fitbit Zip: A Randomized Controlled Pilot Study

      Linck, Donna Teresa; Department of Physiological & Technological Nursing (5/22/2018)
      Physical inactivity is a global pandemic. Six percent of all deaths globally (approximately 3.2 million people) are the result of insufficient physical activity, and 80% of adolescents worldwide do not get the recommended levels of daily physical activity. Depression is a major cause of disability worldwide and is a significant disease of burden for most age groups. Female adolescents are more than twice as likely to experience depressive symptoms as their male counterparts. The primary purpose of this randomized controlled pilot study was to determine if the use of electronic activity monitors, specifically Fitbit Zips, and daily step goals would increase physical activity participation in female adolescents. The secondary purpose was to determine if participation in a 12-week intervention using Fitbit Zips together with step goals would reduce depressive symptoms in female adolescents. The tertiary purpose was to determine the feasibility of recruiting and retaining female adolescents (80% or more) in the study and having them adhere to the research protocol. There were no available research studies examining physical activity and depressive symptoms in female adolescents using Fitbit Zips as an intervention to increase physical activity and decrease depressive symptoms. A convenience sample of 44 female adolescents from two church youth groups in the southeastern United States participated in the study. The mean age of the participants was 16.6 years. Psychosocial variables such as self-efficacy, social support, and commitment to a plan of action were assessed. Using mixed model analysis, no significant differences (p = .678) were found between the experimental (Fitbit-E) and control groups (Fitbit-C) on average median steps per day. The Fitbit-C group had 6,088.3 (SE = 668.6) average median steps per day at baseline, but only had 2,783.7 (SE = 698) average median steps per day at posttest. The Fitbit-E group had a lesser decline with 6,279.1 (SE = 661) average median steps per day at baseline and 4,339.4 (SE = 728) average median steps per day at posttest. Both groups’ depression scores, as measured by the CES-D, decreased from pretest to posttest, indicating an improvement in depressive symptoms. However, the difference between the two groups on depression scores was not statistically significant (p = .425). Post hoc pairwise comparisons yielded statistically significant decreases in depression scores for the Fitbit-C group (p = .002) and for the Fitbit-E group (p < .001) from pretest to posttest. Additionally, 42 out of 44 participants (95%) completed final CES-D surveys, and 35 out of 44 (79.5%) had some final step count data at post-test. Therefore, it was feasible to recruit and retain 80% of the participants in this RCT pilot study, and they did adhere to the protocol. This study helps bring to light the importance of promoting physical activity and assessing for depressive symptoms in the female adolescent population. Although there were no significant differences between the experimental and control groups on depressive symptoms for the 12-week intervention period, within each group there were significant decreases in depressive symptoms. The results from this study provide the groundwork to further investigate the impact of EAMs on physical activity and depressive symptoms in female adolescents.
    • The fenestrations of serious membranes in relation to lymphatic absorption

      Williams, William B.; Department of Anatomy (1971-06)
    • Fibroblast Attachment to Root-End Filling Materials

      Robinson, Sylvester Carlton; Department of Oral Biology (Medical College of Georgia, 1993-07)
    • FLAGELLAR CHAPERONES AND CONTROL OF CAMPYLOBACTER JEJUNI MOTILITY

      Fiedler, Jarred; Department of Biochemistry and Molecular Biology (2018-11)
      Campylobacter jejuni is a leading cause of bacterial gastroenteritis, with an annual incidence of 140 million cases globally and 1.3 million cases in the United States. Approximately 1/1000 of C. jejuni infections lead to the onset of Guillain-Barré Syndrome, the world’s leading cause of acute paralysis. While the pathogenic mechanisms of C. jejuni are incompletely understood, it is known that flagellar motility is a primary virulence factor. Flagella are involved in host cell adherence and invasion, biofilm formation, and chick colonization. Flagellar assembly is dependent on the coordinated regulation of flagellar subunit synthesis via transcriptional and post-transcriptional regulators, as well as flagellar chaperones which maintain flagellar subunits in an unfolded state. In C. jejuni, the post-transcriptional regulator CsrA regulates flagellar biogenesis in C. jejuni by binding to the mRNA for flaA, repressing FlaA synthesis. CsrA regulatory activity on flagellar and non-flagellar targets is predicted to be modulated by protein-protein interactions with the flagellar chaperone FliW. Both FliW and a second flagellar chaperone FliS are predicted to participate in flagellar assembly by binding to FlaA. Therefore, we investigated the roles of FliW and FliS in CsrA regulation and flagellar biogenesis by constructing and characterizing a fliS mutant of C. jejuni strain 81-176, and by testing for the presence of protein-protein interaction(s) among CsrA, flagellin, and flagellar chaperones. We created an in-frame deletion mutant of fliS, and determined that the deletion of fliS resulted in a loss of motility and reduced the capacity of C. jejuni to autoagglutinate and form biofilm. We also used a bacterial two-hybrid system to study possible binding among the flagellarrelated proteins FlaA, FliS, FliW, and CsrA. Additionally, we performed deletion analysis of fliW in pT25, with the goal of identifying the region of FliW that mediates binding to CsrA. CsrA bound to full-length FliW, but no other protein-protein interactions were evident using the two-hybrid system. Surprisingly, CsrA did not interact with fragments of FliW, suggesting that the CsrA-binding site of FliW may be complex. These results show that flagellar biogenesis is accomplished by interactions of flagellar chaperones that link motility with the regulation of Campylobacter pathogenesis-related properties.
    • Fluoride metabolism : effect of caffeinated beverages / by Xiaoyan Chen.

      Chen, Xiaoyan; Department of Oral Biology (1992-05)
    • Follicle stimulating hormone β in reproductive dysfunction

      Clark, Andre Douglas; Medical College of Georgia (Augusta University, 2001-11)
    • Fracture mechanics of dental resin composites

      Kovarik, Robert; Medical College of Georgia (Augusta University, 1991-03)
    • Freeze Filtration: Description and Evaluation of a Method for Obtaining Samples of Liquid Phase From Frozen Solutions

      Bayer, Dirk; N/A (Medical College of Georgia, 1989-09)
      The objective of this study was to develop a method for sampling the liquid phase of frozen solutions (i.e. the remaining liquid between ice crystals and other solids) for subsequent chemical analysis in order to determine the extent of ice formation and other physical-chemical effects of freezing upon solutions. Such information could enhance the development of cryoprotective agents (CP As). which would allow the frozen long term preservation of organs for transplantation. The traditional thermometric/ calorimetric methods for the measurement of ice formation are susceptible to bias by composition change of the liquid phase caused by secondary solid phase formations (i.e. solids besides ice). They are not able to determine the nature Df such composition changes, and some changes, like that of the pH, will go unnoticed. The new method uses subatmospheric pressure to aspirate liquid phase from a cooled sample holder into a collection vial. "Freeze Filtration" has been tested on four well-established cryoprotective agents comparing measurements in this study with literature values on these chemicals. Remarkable accuracy and repeatability have been achieved. Deviations from published values depend on the cryoprotectant used, which suggests a CPA-dependent methodical difference that may be rooted in bias within the literature values. Cells and solute precipitates can be isolated along with liquid phase, and the freeze-elevated concentrations of Na+, K+, Ca2+, and H+ of a single sample have been measured. Freeze Filtration differs from the older methods by providing a simple mode of operation, low cost, the ability to determine composition changes, and the ability to serve as a physical-chemical reference during actual cryosurvival studies. It is directly demonstrated that freezing at velocities and sample sizes applicable to organ freezing can result in substantial pH changes in the liquid phase and the precipitation of solutes. The data also indicate that 1,3-butanediol is not a good cryoprotectant.
    • From Adipokines to Atherosclerosis: The Role of Adipose Tissue in Inflammation and Etiology of Vascular Disease

      Bundy, Vanessa; Vascular Biology Center (2007-04)
      The prevalence of overweight and obese has steadily increased over the years among males and females of all ages, all racial and ethnic groups, and all educational levels. Recent studies have established adipose tissue as a dynamic, endocrine organ with the capacity to secrete a number of adipokines which may act directly upon the vasculature to stimulate adhesion molecule expression and exacerbate vascular disease. Our aim was to elucidate the associations of vasoactive pro- and anti- inflammatory factors, including adhesion molecules, with adiposity, blood pressure and endothelial function, and to distinguish race and sex variations in these relationships. To accomplish this, we expanded upon existing measurements within a Georgia Prevention Institute cross-sectional study entitled Lifestyle, Adiposity & Cardiovascular Health in Youths (LACHY) by adding two cardiovascular disease risk factor domains: inflammation and vascular adhesion. Our model included measurements of adiposity, adiponectin, C-reactive protein, leptin, insulin, resistin, tumor necrosis factor-a, interleukin-6, intercellular adhesion molecule-1, vascular cell adhesion molecule-1, blood pressure and endothelial-dependent arterial dilation. Our findings include numerous race and sex differences in the concentration of circulating risk factors along with significant interactions between them and measurements of adiposity. However, we did not find circulating cardiovascular disease risk factors or their concentration differences to be significantly associated with blood pressure or endothelial function. We believe this to be largely due to the fact that our subjects were young and apparently healthy at time of measurement. Overall, our findings provide insight into the relationships between adiposity, inflammation and cardiovascular outcomes in black and white, male and female adolescents. Future studies are needed to further elucidate these relationships and how they may change over time.