• Aortic Calcification and Femoral Bone Density Are Independently Associated with Left Ventricular Mass in Patients with Chronic Kidney Disease

      Chue, Colin D.; Wall, Nadezhda A.; Crabtree, Nicola J.; Zehnder, Daniel; Moody, William E.; Edwards, Nicola C.; Steeds, Richard P.; Townend, Jonathan N.; Ferro, Charles J.; Shi, Xing-Ming; et al. (2012-06-18)
      Background: Vascular calcification and reduced bone density are prevalent in chronic kidney disease and linked to increased cardiovascular risk. The mechanism is unknown. We assessed the relationship between vascular calcification, femoral bone density and left ventricular mass in patients with stage 3 non-diabetic chronic kidney disease in a cross-sectional observational study.
    • APOROSA OCTANDRA: STUDY THE PROTECTIVE EFFECTS OF ITS BARK EXTRACT AGAINST D-GALACTOSE INDUCED COGNITIVE IMPAIRMENT AND OXIDATIVE STRESS IN MICE AND ITS PHYTOCHEMICAL INVESTIGATION

      Schinder, Sonya; Department of Chemistry and Physics; Panda, Silva; Augusta University (2019-02-13)
      Aging is a multifarious natural process, linked with several biochemical and morphological variations in the biological system. Aging not only challenges the increased vulnerability as well as homeostasis network to the cognition and locomotion but also to physical, mental or social activities. Medicinal plants have been used since ancient time to cure and prevent various diseases. Several natural compounds such as isoflavones, anthocyanins, and catechins isolated from plant sources act as a potent antioxidant against ROS (Reactive Oxygen Species).�Antioxidants, especially natural antioxidants are recommended for the prevention of aging. In this study, we utilized an unexplored traditional medicinal plant�Aporosa octandra�(Buch.-Ham. ex D. Don) that�belongs to the family�Euphorbiaceae,�sub-family Phyllanthaceae that is shrub to tree, up to 15 m high and comprises of 50 species, which are distributed throughout Asian regions. This plant is enlisted as a medicinal plant and is used for centuries in the Ayurvedic system. We investigated phytochemical contents of the plant and evaluated the biological activity.
    • The Application of Low-Cost, Close-Range Photogrammetry in Dentistry

      Patel, Mohit; Mettenburg, D.; Biological Sciences, Restorative Sciences (Augusta University Libraries, 2020-05-05)
      This item presents the abstract for a poster presentation at the 21st Annual Phi Kappa Phi Student Research and Fine Arts Conference.
    • Applications of Digital Dentistry in the Esthetic Zone

      Yeung, Matthew; General Dentistry (2020-02)
      To demonstrate the benefits of incorporating digital technologies into treatment planning restorations in the anterior maxilla.
    • Aquatic Therapy Strength Training Benefits for the Leg Strength of Children with Cerebral Palsy

      Quick, Elizabeth; Department of Biological Sciences (Augusta University, 2015-05)
      The purpose of this thesis is to track the aspects and results of applying aquatic therapy strength training exercises to children with cerebral palsy and determine whether or not the therapy is beneficial for leg strengthening in comparison to a usual physical therapy clinical setting. The experiment was carried out twice a week, for 12 weeks. Two groups of six children with cerebral palsy participated in the experiment, in which they were administered leg strengthening exercises.
    • Are NFL teams getting the most out of their wins? The Efficiency of Year End Revenues of Ten NFL Teams

      Gonzales, Savanna; Thompson, Mark; Hull College of Business; Thompson, Mark; Hull College of Business; Hoffman, Todd; Department of English and Foreign Languages; Hunt, David; Pamplin College; Augusta University (2018-02-12)
      Major sports have taken over many prominent industries in today's world. With the economic impact of athletics comes its evolution from a spectator event into a business. Each team in the major leagues is now not only pressured to produce winsbut as a business, they must also bring in revenue. This means that efficiencyof funds is a vital goal of team managers and financial specialists. Thisresearch projectexaminesthe effects of various factors on year-end revenues for the top ten most valuable teams in the National Football League. Through the use of a DEA model that analyzes such inputs as income, team record and stand out players we areable to determine how efficiently each team is performing based on their revenues, or the output. Of the 10 teams studied, 5 were deemed efficient while 5 were deemed inefficient.Teams that didnot see successful revenue reports were analyzed based on their weaknesses and offered recommendations on which to improve where efficient teams were used a comparison. Ultimately, the goal of this research is to identify factors to improve revenue efficiency across the league as a whole by looking at the top performing teams (or best practices).
    • Are NFL teams getting the most out of their wins? The Efficiency of Year End Revenues of Ten NFL Teams

      Gonzales, Savanna; Department of Management and Marketing (Augusta University, 2018-05)
      Major sports have taken over many prominent industries in today's world. With the economic impact of athletics comes its evolution from a spectator event into a business. Each team in the major leagues is now not only pressured to produce winsbut as a business, they must also bring in revenue. This means that efficiencyof funds is a vital goal of team managers and financial specialists. Thisresearch projectexaminesthe effects of various factors on year-end revenues for the top ten most valuable teams in the National Football League. Through the use of a DEA model that analyzes such inputs as income, team record and stand out players we areable to determine how efficiently each team is performing based on their revenues, or the output. Of the 10 teams studied, 5 were deemed efficient while 5 were deemed inefficient.Teams that didnot see successful revenue reports were analyzed based on their weaknesses and offered recommendations on which to improve where efficient teams were used a comparison. Ultimately, the goal of this research is to identify factors to improve revenue efficiency across the league as a whole by looking at the top performing teams (or best practices).
    • The Art of Conservation: The Federal Duck Stamp

      Harris, Kirstyn; Department of History, Anthropology, & Philosophy (Augusta University, 2019-12)
      President Franklin Roosevelt signed the Duck Stamp Act into law in 1934. The Duck Stamp Act states that any waterfowl hunter over the age of 16 years old must buy a Federal Duck Stamp and that the sales from the stamp go to the Migratory Bird Conservation Fund. In the beginning, the government selected an artist to paint the stamp. After a few years of debates, there was a proposal to form the Federal Duck Stamp contest in which anyone could participate. This is the longest-running government controlled contest in the United States.
    • Artificial Chromosome Transgenesis Reveals Long-Distance Negative Regulation of ragl in Zebrafish

      Jessen, Jason R.; Department of Biochemistry and Molecular Biology (1999-11)
      Despite the essential roles played by the recombination activating genes (ragl and rag2) during V(D)J recombination, the mechanisms that restrict their expression to lymphoid cells are undefined. Using a novel approach to achieve artificial chromosome transgenesis in zebrafish, we demonstrate that distal regulatory elements are critical to suppress ragl expression in inappropriate tissues. In contrast to smaller reporter gene constructs, 125 and 75 kb artificial chromosomes containing the zebrafish rag genomic locus directed GFP expression in a pattern reflective of endogenous rag 1. Mapping experiments identified a positive element 5' of ragl that enhances GFP expression in both lymphoid and non-lymphoid tissues and a negative element 5' of ra g l that specifically suppresses GFP expression in the skeletal muscle. Our transgenic zebrafish also express GFP in olfactory neurons which we show represent an authentic ra g l expression site in zebrafish.
    • Asian Pride & Prejudice: The Relationship Between Ethnic Identity & Mental Illness Stigma

      Fang, Shawn; Department of Psychological Sciences (2017-03)
      As Asian health professionals increasingly diversify the medical workplace, their early upbringing – characterized by acculturation, social identity, and “face” concern – may potentially exert influence on their own perceptions of mental illness. Such perceptions, often stigmatizing against others, could impact provision of medical care to the community at large. This study examines the hypothesized correlation between 1) strength of ethnic identity – as measured by an adapted version of the East Asian Ethnic Identity Scale – and 2) degree of mental illness stigma – as measured by an adapted pre-medical student version of the Mental Illness: Clinician’s Attitudes Scale. Conclusions will stem from statistical analysis of self-report online survey responses from Asian full-time college students enrolled in healthcare-oriented undergraduate studies (i.e. medicine, nursing, physical therapy, etc.). The broad aim of this study is to discern how the influence of ethnic identity could potentially interact with and predict mental illness stigma in the future patient care provided by aspiring Asian healthcare professionals. My presentation will discuss the literature-based premise for studying the intersection of culture and stigma, and I will summarize proposed protocol for the research process.
    • Assessing Blackworms as a Model for Studying AVM

      Frazier, Eric; Wiley, Faith; Department of Biological Sciences (2017-03)
      Avian Vacuolar Myelinopathy (AVM) is a neurological disease that affects certain species of birds within the Southeastern region of the United States. Research suggests that this disease is linked to the consumption of a cyanobacterial species inhabiting hydrilla, an invasive aquatic weed. The objective of this experiment is to assess whether blackworms are a good model for studying AVM. Blackworms are invertebrate organisms usually found in marshes, swamps and ponds. These organisms are commonly used in toxicity testing due to many factors such as having a low level of maintenance and being cost efficient. Blackworms were initially exposed to concentrated extracts of hydrilla/cyanobacteria for a period of five days. There was no difference in mortality between control and treatment worms. Two additional experiments are currently being conducted to examine potential sublethal effects. Regrowth of blackworm body segments and rate of asexual reproduction are being examined in worms exposed to the hydrilla extracts, as well as to water and sediment collected from Lake Thurmond, GA during an AVM event.
    • Assessing Local Parks For Their Infrastructure Availability And Use Along With Physical Activity Levels Of The Local Children

      Shabu, Elizabath; Department of Kinesiology (Augusta University, 2020-05)
      This research project assessed public park physical activity infrastructure use in Richmond and Columbia Counties. Prior research has shown that children not only enjoy outdoor time, but also consider parks as a place for socializing. Furthermore, research has shown that playground time positively impacts children’s imagination. The playground also aids in the physical fitness of children by offering interactive experiences that can add to the recommended 60 minutes of physical activity a day. Park assessments were conducted utilizing the Physical Activity Resource Assessment (PARA) Tool and found that overall, parks in both counties were well taken care of. Additionally, there was a wide variety of amenities available to utilize. There were some areas of concern in the parks, however, including cigarette buds, alcohol containers, trash, and cracked sidewalks. In both counties, parks were observed to see how much children utilized the playground equipment. Observations concluded that the majority of children utilized the different variety of equipment, with the swings and slides being the most common. In conclusion, this presentation will describe the diversity of amenities, challenges in maintenance, and the overall use of public parks in both Richmond and Columbia Counties.
    • Assessing Local Parks for their Infrastructure, Issues, and Use

      Shabu, Elizabath; Kinesiology (Augusta University Libraries, 2020-05-04)
      This item presents the abstract for a poster presentation at the 21st Annual Phi Kappa Phi Student Research and Fine Arts Conference.
    • Assessing Medical Students Knowledge in Diagnosis and Initial Treatment of Depression

      Youssef, Nagy A.; Thomas, Andria; Ange, Brittany; Yassa, Mark; Boswell, Elizabeth; Wallach, Paul M.; Department of Psychiatry and Health Behavior; Department of Psychological Sciences; Department of Chemistry and Physics; Augusta University (2017-03)
      Depression is one of the leading causes of premature death, and one of the highest burdens of overall disability. Depression rates are around 13% in primary care settings. Depressive episodes are still underdiagnosed and undertreated. Factors that contribute to this include lack of detailed knowledge, lack of confidence in treatments among others. Thus, addressing these gaps would improve patients care. Moreover, bipolar depression can be difficult to distinguish from unipolar; and requires a different treatment. Improving education of students in these areas would improve care for patients. Aims are as follows: 1) assess students’ level of confidence and knowledge in diagnosing and treating depression, and any barriers to gaps in knowledge, 2) assess students’ knowledge in differential diagnosis of depression and any barriers to gaps in knowledge. We are assessing these by an online survey on website used by Medical College of Georgia for student questionnaires, sent to all third-year medical students after internal medicine rotation. The survey is sent through academic affairs office. This will provide valuable knowledge in improving our education and curriculum for the new generation of physicians.
    • Assessing the Validity of Vitamin D Supplementation in Patients with Symptomatic Knee Osteoarthritis

      Campbell, Caroline; Harris, Matthew; Littlejohn, Rodney; Paletta, Nina; Stone, David; Williams, Ashley; Medical College of Georgia (2016-05)
      In an older adult population, does supplementation of 25-hydroxyvitamin D for patients with symptomatic knee osteoarthritis with low serum vitamin D alleviate symptoms of the disease?
    • Assessment of p65 in the Novel Microglial NF-κB Animal Model

      Frerichs, Ryan; Department of Biological Sciences (Augusta University, 2021-05)
    • Assessment of Renal Ischemia Reperfusion Induced Injury in Male and Female Rats

      Crislip, Gene Ryan; Department of Physiology (2017)
      Acute kidney injury (AKI) is a clinical problem often induced by ischemia reperfusion (IR). Males are reported to have worse outcomes following IR compared to females based on measurements of blood urea nitrogen and creatinine. However, these markers are produced at different levels depending on body mass. The goal of Aims 1 and 2 was to do a complete assessment of the impact of sex on IR to establish a model that displays a sex difference. We measured multiple markers, including inulin clearance which is the gold standard of determining renal function. We determined there is no sex difference in response to IR after 24 hours. However, males had impaired renal function, higher vascular congestion and tubular injury than females 7 days following IR. A consequence of vascular congestion and tubular injury is fluid leakage into interstitial space, which increases renal volume. The goal of Aim 3 was to determine if ultrasound could be used as a tool to detect progressive changes in regional kidney volume following IR. To do this, we compared renal volume measurements with stereological assessment and examined the use of renal volume as an injury marker following IR. We verified the use of ultrasound to monitor renal volume after IR and the changes in volume correlated with the extent of medullary injury. Limiting vascular congestion improves recovery following IR. Pericytes are contractile cells that line the vessels in the renal medulla that are prone to congestion following IR. The goal of Aim 4 was to determine the role of renal pericytes following IR. To do this, we decreased pericytes in rats before IR to determine if this effected injury. We found that lower pericyte density was associated with greater vascular congestion following IR, additionally, males lose more pericytes than females. From these studies, we concluded that there was no sex difference in IR induced injury after 24 hours, however, following 7 days males had poorer recovery than females. We hypothesize that this poorer recovery is attributed to less pericytes in males following IR resulting in the inability to reduce vascular congestion compared to females.
    • Assessments Evaluating the Relationship Between Psychosocial Factors and Upper Extremity Trauma: A Scoping Review

      Coleman, Isabelle; Glaze, Morgan; Griffin, Caroline; Holbrooks, Sarah Beth; Moore, Kristen; Department of Occupational Therapy (Augusta University, 2021-09)
      Objectives of Presentation: At the conclusion of this presentation, attendees will: ● Identify 3 current assessments available that evaluate the psychosocial components of upper extremity (UE) recovery after trauma. ● Discuss 3 of the most common types of psychosocial challenges often experienced by individuals with UE trauma. Clinical/Research Question: What assessments are available for examining the relationships between psychosocial factors and UE trauma during rehabilitation of adults with UE trauma?
    • The association between fitness, metabolic levels, and cognitive performance in an older population

      Dojack, Amanda; Department of Kinesiology (Augusta University, 2018-05)