• The Gs-Linked Receptor GPR3 Inhibits the Proliferation of Cerebellar Granule Cells during Postnatal Development

      Tanaka, Shigeru; Shaikh, Imran Mohammed; Chiocca, Ennio Antonio; Saeki, Yoshinaga; Mei, Lin; Department of Neurology; College of Graduate Studies (2009-06-15)
      Background: During postnatal murine and rodent cerebellar development, cerebellar granule precursors (CGP) gradually stop proliferating as they differentiate after migration to the internal granule layer (IGL). Molecular events that govern this program remain to be fully elucidated. GPR3 belongs to a family of Gs-linked receptors that activate cyclic AMP and are abundantly expressed in the adult brain.