Dissecting the Roles of Reactive Oxygen Species in Cardiovascular Disease

Hdl Handle:
http://hdl.handle.net/10675.2/579777
Title:
Dissecting the Roles of Reactive Oxygen Species in Cardiovascular Disease
Authors:
Wang, Yusi
Abstract:
Cardiovascular disease remains the leading cause of death in the USA. While much has been learned about the root causes, the underlying mechanisms remain incompletely understood. In particular, elevated levels of reactive oxygen species (ROS) have been observed in the vasculature of blood vessels from animal models and humans with hypertension, atherosclerosis and diabetes. The importance of ROS to cardiovascular disease and the mechanisms by which it alters the function of cells of the cardiovascular system are the goals of this dissertation.
Affiliation:
Vascular Biology Center
Issue Date:
Sep-2015
URI:
http://hdl.handle.net/10675.2/579777
Type:
Dissertation
Appears in Collections:
Theses and Dissertations; Vascular Biology Center Theses and Dissertations

Full metadata record

DC FieldValue Language
dc.contributor.authorWang, Yusien
dc.date.accessioned2015-10-15T16:33:10Zen
dc.date.available2015-10-15T16:33:10Zen
dc.date.issued2015-09en
dc.identifier.urihttp://hdl.handle.net/10675.2/579777en
dc.description.abstractCardiovascular disease remains the leading cause of death in the USA. While much has been learned about the root causes, the underlying mechanisms remain incompletely understood. In particular, elevated levels of reactive oxygen species (ROS) have been observed in the vasculature of blood vessels from animal models and humans with hypertension, atherosclerosis and diabetes. The importance of ROS to cardiovascular disease and the mechanisms by which it alters the function of cells of the cardiovascular system are the goals of this dissertation.en
dc.rightsCopyright protected. Unauthorized reproduction or use beyond the exceptions granted by the Fair Use clause of U.S. Copyright law may violate federal law.en
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectsuperoxideen
dc.subjectCircadian Rhythmen
dc.subjectReactive Oxygen Species (ROS)en
dc.subjectinflammationen
dc.titleDissecting the Roles of Reactive Oxygen Species in Cardiovascular Diseaseen
dc.typeDissertationen
dc.contributor.departmentVascular Biology Centeren
dc.description.advisorFulton, Fultonen
dc.description.committeeStepp, David; Venema, Richard; Rudic, Dan; Ramesh, Ganesanen
dc.description.degreeDoctor of Philosophy with a Major in Vascular Biologyen
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