Gene-Environment Interaction Modulates Schizophrenic Endophenotypes in Heterozygous Reeler Mice

Hdl Handle:
http://hdl.handle.net/10675.2/346174
Title:
Gene-Environment Interaction Modulates Schizophrenic Endophenotypes in Heterozygous Reeler Mice
Authors:
Howell, Kristy R. ( 0000-0002-0872-5335 )
Abstract:
Aim 1: To determine the effect of chronic stress on the VEGF signaling pathway. Aim 2: To determine the effects of prenatal hypoxia on VEGF signaling, behavioral activities, blood flow, and brain volume in heterozygous reeler mice during early adulthood. Aim 3: To evaluate long lasting effects of prenatal hypoxia on VEGF signaling, behavioral activities, blood flow, and brain volume in heterozygous reeler mice. Aim 4: To determine the correlation between serum VEGF levels and brain volumes in schizophrenia subjects.
Affiliation:
Department of Psychiatry and Health Behavior
Issue Date:
Jul-2013
URI:
http://hdl.handle.net/10675.2/346174
Additional Links:
http://ezproxy.augusta.edu/login?url=http://search.proquest.com/docview/1448689087?accountid=12365
Type:
Dissertation
Appears in Collections:
Department of Psychiatry and Health Behavior: Faculty Research and Presentations; Theses and Dissertations

Full metadata record

DC FieldValue Language
dc.contributor.authorHowell, Kristy R.en
dc.date.accessioned2015-03-05T04:41:50Zen
dc.date.available2015-03-05T04:41:50Zen
dc.date.issued2013-07en
dc.identifier.urihttp://hdl.handle.net/10675.2/346174-
dc.description.abstractAim 1: To determine the effect of chronic stress on the VEGF signaling pathway. Aim 2: To determine the effects of prenatal hypoxia on VEGF signaling, behavioral activities, blood flow, and brain volume in heterozygous reeler mice during early adulthood. Aim 3: To evaluate long lasting effects of prenatal hypoxia on VEGF signaling, behavioral activities, blood flow, and brain volume in heterozygous reeler mice. Aim 4: To determine the correlation between serum VEGF levels and brain volumes in schizophrenia subjects.en
dc.relation.urlhttp://ezproxy.augusta.edu/login?url=http://search.proquest.com/docview/1448689087?accountid=12365en
dc.rightsCopyright protected. Unauthorized reproduction or use beyond the exceptions granted by the Fair Use clause of U.S. Copyright law may violate federal law.en
dc.subjectSchizophreniaen
dc.subjectChronic Stressen
dc.subjectVEGFen
dc.subjectPrenatal Hypoxiaen
dc.titleGene-Environment Interaction Modulates Schizophrenic Endophenotypes in Heterozygous Reeler Miceen
dc.typeDissertationen
dc.contributor.departmentDepartment of Psychiatry and Health Behavioren
dc.description.advisorPillai, Anilkumaren
dc.description.committeeDhandapani, Kris; Terry, Alvin; Mei, Lin; Buckley, Peteren
dc.description.degreeDoctor of Philosophy (Ph.D.)en
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