Scholarly Commons @Augusta University
Scholarly Commons is Augusta University's institutional repository and aims to preserve and distribute scholarly works and historical documents generated by the University and its legacy institutions. Scholarly Commons is managed by the University Libraries. For more information about the repository, please see the About page or contact Jennifer Davis, Scholarship and Data Librarian, at firstname.lastname@example.org.
Communities in DSpace
Select a community to browse its collections.
CURS Connection November 2022Table of Contents: Katelinn Jones; Reflection: National Mentor Day by Jordan Moratin; Summer Scholars Program 2023 - Call for Proposals; Last Call for Research Distinctions Fall 2022; Spring 2023: CURS Course Registration; Initial Chemical Safety Training Spring 2023; Upcoming CURS Events; CURS T-shirts for Sale; CURS Calendar.
The Effect of Buccal versus Vaginal Misoprostol on Time to Favorable Simplified Bishop ScoreOBJECTIVE: To evaluate whether buccal or vaginal Misoprostol provides a statistically significant shorter time interval to a favorable simplified Bishop score, and to determine if there is a significant difference in time to delivery between these two modes of administration. DESIGN: Retrospective cohort study via chart review SETTING: Augusta University, Augusta, Georgia PATIENTS: Mothers who delivered full term singleton gestations after being admitted for induction of labor at Augusta University from January 1, 2015 to July 31, 2018 with an initially unfavorable simplified Bishop score on cervical exam. Exclusion criteria: (1) Favorable initial simplified Bishop score (>5) at the time of onset of induction of labor, (2) multiple gestation, (3), pre-term gestation and (4) use of multiple different modalities for cervical ripening. INTERVENTION: Medical records were reviewed to determine if mothers meeting the criteria above had a statistically significant difference in time to favorable simplified Bishop score using vaginal versus buccal Misoprostol and/or a statistically significant difference in time to delivery. MAIN OUTCOME MEASURE: The primary outcome was time to favorable simplified Bishop score (>5). The secondary outcome was time to delivery. RESULTS: • Primary outcome- no significant difference between the buccal and vaginal groups in median time from initial Misoprostol dose to time of favorable simplified Bishop score (p=0.371). • Secondary outcome- no significant difference between the buccal and vaginal groups in median time from initial Misoprostol dose to time of delivery (p=0.371). • No significant difference in complication rate between the buccal and vaginal groups (p=0.199).
Pfizer COVID-19 Vaccine ExplainedMedical students are challenged to apply their biochemistry foundation towards a greater understanding of the molecular mechanisms involved in pathophysiological processes. Addressing the gap between basic sciences and clinical sciences is imperative, especially in light of educating the medical community about COVID-19 and the importance of vaccination. This video demonstrates how PyMol, a molecular graphics tool, can be used to visualize the three-dimensional structure of proteins on the SARS-CoV-2. During the COVID-19 pandemic, this video was posted on the MCG COVID Response Page and was used to teach the medical community about the SARS-CoV-2 virus and how the Pfizer vaccine works. Exploring a detailed 3D model of the virus allows students to study the spike protein amino acid sequence on the virus, see how mutations in the virus change its interaction with the ACE2 human receptor, and consequently, visualize the conformational changes that the spike protein undergoes as it fuses with the host cell. It is important that medical students learn how to utilize available technologies to critically analyze the relationship between protein structure and function and understand how this interaction plays a role the COVID-19 mutations responsible for the pandemic.
CURS Connection October 2022Table of Contents: Spotlight: CURS Student Assistants; Fall Grant Recipients; Ask a CURS Ambassador; Spring 2023: CURS Course Registration; National Mentoring Day; CURS Game Night; CURS T-shirts for Sale; 2022 Georgia Undergraduate Research Conference; CURS Calendar.
The Flight of the Junky: Existential Posthumanism and Immanent Life in Early BurroughsWilliam Burroughs early book Junky is generally separated from his later experimental fiction. Stylistically it accords much more to realism than the postmodern aleatory method he later innovated. However, Burroughs’ preoccupation with resisting all forms of subjectification, his disenchantment with bourgeois life and his simultaneous literal and tropic use of addiction as a form of flight from powers of normalization and conformity are strongly present in this early work. This paper explores Junky on three fronts. First, it shows the novel as an elaboration of a posthumanist existentialism by emphasizing the materiality of the body through Burroughs’ explanation of the physiological mechanisms of addiction. Through this existentialist posthumanism, the novel critically responds to Sartrian existentialism, which was so fashionable at the time of Burroughs’ writing, and repudiates the Jeffersonian idealization of the transcendental subject and its middle class figurations. The emphasis on the material body simultaneously challenges post-structuralist renderings of Burroughsian readings. This leads to a conception of strategies of flight from all forms of conformity by utilizing Deleuze and Guattari’s notion of the Body without Organs and immanent Life. Junk is a vehicle of flight and self-affirmation, a means of highly individualized, libertarian modes of subjective deterritorialization. Addiction and habitual use are not mere uncontrolled thirsts, but forms of actualizing a wholly detached social and independent individual. But the danger of junk lies in its reterritorializing of the body through new assemblages of need and dependence, leading the protagonist to ultimately seek a different mode of escape. Junk illuminates our posthuman existential condition and leads Burroughs to seek new experimental forms of aesthetic expression.