Scholarly Commons @Augusta University

 

Scholarly Commons is Augusta University's institutional repository and aims to preserve and distribute scholarly works and historical documents generated by the University and its legacy institutions. Scholarly Commons is managed by the University Libraries. For more information about the repository, please see the About page or contact Jennifer Davis, Scholarship and Data Librarian, at jdavis14@augusta.edu

 

                                             

 

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AU COVID-19 Research and Scholarship [99]
AU Open Access Pilot Program Awards [8]
AU Syllabi Repository [0]
AU Teaching Commons [6]
Wellstar MCG Health (formerly AU Health) [4]
University Publications [36]
Special Collections and Archives [2303]
  • Faculty Senate Newsletter: The Tea with Dr. T (January 2024)

    Curry-McCoy, Tiana (Augusta University, 2024-01)
  • THOMAS HARDY'S FARFROM THE MADDING CROWD: ANALYZING PHYSICAL, NATURAL, AND NAMING LIMINAL SPACES

    Wescom, Amanda; Augusta University; Augusta State University Honors Thesis (Augusta University, 2005-01-28)
  • LA MASACRE DE LAS BANANERAS: A NEW HISTORICIST APPROACH TO GABRIEL GARCIA MARQUEZ'S ONE HUNDRED YEARS OF SOLITUDE

    Chegwin, Natalya; Augusta University; Augusta State University Honors Thesis (Augusta University, 2005-01-24)
  • Regulating Effects of 11-Deoxycorticosterone on 3beta-Hydroxysteroid Dehydrogenase

    Hutchinson, Emmanuelle; Augusta State University Honors Thesis; Augusta State University Honors Thesis (Augusta University, 2005)
    Regulating Effects of 11-Deoxycorticosterone on 3 beta-Hydroxysteroid Dehydrogenase Progesterone plays a key role in ovulation and the formation of a corpus luteum, although its regulation remains poorly understood. The enzyme 3/J-hydroxysteroid dehydrogenase (3/iHSD) converts pregnenolone to progesterone and thus represents a critical step in progesterone biosynthesis. It has recently been discovered that the primate ovary synthesizes 11-deoxycorticosterone (DOC) in response to an ovulatory gonadotropin stimulus. Blockade of the mineralocorticoid receptor (MR), which serves as the receptor for DOC, prevents gonadotropin-induced progesterone synthesis. It is hypothesized that DOC augments the expression of 3/HSD following an ovulatory stimulus via MR-mediated mechanisms. The current studies were to determine if 3/iHSD is an MR target gene in H295R adrenocortical cells, which are used as a surrogate model of primate ovarian steroidogenesis. The results indicate that an increase in 3^HSD RNA is associated with the Forskolin treatment (receptor agonist), which was expected. The Forskolin treatment was statistically different from Forskolin+Flutamide (FL blocks androgen receptors), which suggests that 3/?HSD is regulated by androgen receptors and not mineralocorticoid receptors (such as the ones in DOC). The results also demonstrate that passage number affects steroidogenic properties of H295R cells.
  • EXPLORING CULTURAL THEMES IN CAJUN POETRY

    Morrison, Matthew; Augusta State University Honors Thesis; Augusta State University Honors Thesis (Augusta University, 2004)

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