Transcranial Doppler measures in patients with sickle cell disease at high risk for stroke and receiving hydroxyurea: the HyRetro ancillary study

Hdl Handle:
http://hdl.handle.net/10675.2/941
Title:
Transcranial Doppler measures in patients with sickle cell disease at high risk for stroke and receiving hydroxyurea: the HyRetro ancillary study
Authors:
Adamkiewicz, Thomas; Odo, Nadine; Kutlar, Abdullah; Kwiatkowski, Janet L; Adams, Robert J
Abstract:
Children with sickle cell disease (SCD) and increased transcranial Doppler sonography velocity measures are at increased risk for stroke. Although chronic transfusion decreases risk tenfold, this form of therapy is burdensome and includes risk of iron overload. Hydroxyurea therapy is effective in preventing SCD complications, although its effect in preventing SCD central nervous system complications is less clear and a matter of current investigation.
Affiliation:
School of Medicine
Publisher:
American Society of Hematology
Issue Date:
Dec-2010
URI:
http://hdl.handle.net/10675.2/941
Language:
en_US
Series/Report no.:
ASH;2010-H03
Sponsors:
NIH/National Center on Minority Health and Health Disparities (NCMHD Southeastern Exploratory Sickle Cell Center of Excellence); and NIH/National Heart, Lung, and Blood Institute
Appears in Collections:
Department of Anesthesiology and Perioperative Medicine: Faculty Research and Presentaions

Full metadata record

DC FieldValue Language
dc.contributor.authorAdamkiewicz, Thomas-
dc.contributor.authorOdo, Nadine-
dc.contributor.authorKutlar, Abdullah-
dc.contributor.authorKwiatkowski, Janet L-
dc.contributor.authorAdams, Robert J-
dc.date.accessioned2013-02-21T22:53:40Z-
dc.date.available2013-02-21T22:53:40Z-
dc.date.issued2010-12-
dc.identifier.urihttp://hdl.handle.net/10675.2/941-
dc.description.abstractChildren with sickle cell disease (SCD) and increased transcranial Doppler sonography velocity measures are at increased risk for stroke. Although chronic transfusion decreases risk tenfold, this form of therapy is burdensome and includes risk of iron overload. Hydroxyurea therapy is effective in preventing SCD complications, although its effect in preventing SCD central nervous system complications is less clear and a matter of current investigation.en_US
dc.description.sponsorshipNIH/National Center on Minority Health and Health Disparities (NCMHD Southeastern Exploratory Sickle Cell Center of Excellence); and NIH/National Heart, Lung, and Blood Instituteen_US
dc.language.isoen_USen_US
dc.publisherAmerican Society of Hematologyen_US
dc.relation.ispartofseriesASH;2010-H03-
dc.subjectSickle cell diseaseen_US
dc.subjectHydroxyureaen_US
dc.subjectTranscranial Doppler ultrasounden_US
dc.titleTranscranial Doppler measures in patients with sickle cell disease at high risk for stroke and receiving hydroxyurea: the HyRetro ancillary studyen_US
dc.contributor.departmentSchool of Medicineen
dc.contributor.corporatenameMorehouse Collegeen_US
dc.contributor.corporatenameDepartment of Anesthesiology and Perioperative Medicineen_US
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