The Early Stage Adjacent Disc Degeneration after Percutaneous Vertebroplasty and Kyphoplasty in The Treatment of Osteoporotic VCFs

Hdl Handle:
http://hdl.handle.net/10675.2/830
Title:
The Early Stage Adjacent Disc Degeneration after Percutaneous Vertebroplasty and Kyphoplasty in The Treatment of Osteoporotic VCFs
Authors:
Qian, Jun; Yang, Huilin; Jing, Juehua; Zhao, Hong; Ni, Li; Tian, Dasheng; Wang, Zhengfei
Abstract:
Background: The purpose of this paper is to determine the early incidence of disc de- generation adjacent to the vertebral body of osteoporotic fracture treated with percutaneous vertebroplasty or balloon kyphoplasty and whether adjacent disc degeneration is accelerated by this two procedures.; Methods: 182 patients with painful vertebral compression fractures were treated. A total of 97 patients were enrolled in this prospective study. 97 patients with a mean age of 65.3 years were classified into control group and surgical treatment group of non-random. 35 patients were in contol group and 62 patients who were performed percutaneous vertebroplasty or balloon kyphoplasty in treatment group. X-ray and Magnetic resonance imaging were done at the first and final visit. The grade of disc degeneration above the fractured vertebral was confirmed by evaluation of bony oedema in the fat suppressed sequences and T2-weighted image of magnetic resonance imaging. The height of degenerative disc was measured on X-ray film.; Results: All patients were followed up two years after the first visit and the follow-up rate was 90.7% (88/97). The incidence of degeneration of adjacent disc above the fractured vertebral was 29.0% (9/31) in control group and 52.6% (30/57) in treatment group. It presented a statistically significant difference between two groups about the incidence of adjacent disc degeneration (P =0.033). The percentage of adjacent disc height reduction in control group was 13.5% and 17.6% in treatment group. Statistically significant difference of VAS score and ODI was not found between the first evaluation postoperatively and the final follow-up in treatment group (P>0.05).; Conclusions: Disc degeneration adjacent to the fractured vertebral is accelerated by VP and BK procedures in the early stage, but clinical outcomes has not been weakened even in the presence of accelerated disc degeneration.
Editors:
Shi, Xing-Ming
Citation:
PLoS One. 2012 Oct 8; 7(10):e46323
Issue Date:
8-Oct-2012
URI:
http://hdl.handle.net/10675.2/830
DOI:
10.1371/journal.pone.0046323
PubMed ID:
23056283
PubMed Central ID:
PMC3466231
Type:
Article
ISSN:
1932-6203
Appears in Collections:
Department of Pathology: Faculty Research and Presentations

Full metadata record

DC FieldValue Language
dc.contributor.authorQian, Junen_US
dc.contributor.authorYang, Huilinen_US
dc.contributor.authorJing, Juehuaen_US
dc.contributor.authorZhao, Hongen_US
dc.contributor.authorNi, Lien_US
dc.contributor.authorTian, Dashengen_US
dc.contributor.authorWang, Zhengfeien_US
dc.contributor.editorShi, Xing-Ming-
dc.date.accessioned2012-10-26T20:35:13Z-
dc.date.available2012-10-26T20:35:13Z-
dc.date.issued2012-10-8en_US
dc.identifier.citationPLoS One. 2012 Oct 8; 7(10):e46323en_US
dc.identifier.issn1932-6203en_US
dc.identifier.pmid23056283en_US
dc.identifier.doi10.1371/journal.pone.0046323en_US
dc.identifier.urihttp://hdl.handle.net/10675.2/830-
dc.description.abstractBackground: The purpose of this paper is to determine the early incidence of disc de- generation adjacent to the vertebral body of osteoporotic fracture treated with percutaneous vertebroplasty or balloon kyphoplasty and whether adjacent disc degeneration is accelerated by this two procedures.en_US
dc.description.abstractMethods: 182 patients with painful vertebral compression fractures were treated. A total of 97 patients were enrolled in this prospective study. 97 patients with a mean age of 65.3 years were classified into control group and surgical treatment group of non-random. 35 patients were in contol group and 62 patients who were performed percutaneous vertebroplasty or balloon kyphoplasty in treatment group. X-ray and Magnetic resonance imaging were done at the first and final visit. The grade of disc degeneration above the fractured vertebral was confirmed by evaluation of bony oedema in the fat suppressed sequences and T2-weighted image of magnetic resonance imaging. The height of degenerative disc was measured on X-ray film.en_US
dc.description.abstractResults: All patients were followed up two years after the first visit and the follow-up rate was 90.7% (88/97). The incidence of degeneration of adjacent disc above the fractured vertebral was 29.0% (9/31) in control group and 52.6% (30/57) in treatment group. It presented a statistically significant difference between two groups about the incidence of adjacent disc degeneration (P =0.033). The percentage of adjacent disc height reduction in control group was 13.5% and 17.6% in treatment group. Statistically significant difference of VAS score and ODI was not found between the first evaluation postoperatively and the final follow-up in treatment group (P>0.05).en_US
dc.description.abstractConclusions: Disc degeneration adjacent to the fractured vertebral is accelerated by VP and BK procedures in the early stage, but clinical outcomes has not been weakened even in the presence of accelerated disc degeneration.en_US
dc.subjectResearch Articleen_US
dc.subjectBiologyen_US
dc.subjectAnatomy and Physiologyen_US
dc.subjectMusculoskeletal Systemen_US
dc.subjectMuscleen_US
dc.subjectMuscle Biochemistryen_US
dc.subjectMusculoskeletal Anatomyen_US
dc.subjectMedicineen_US
dc.subjectAnatomy and Physiologyen_US
dc.subjectMusculoskeletal Systemen_US
dc.subjectMuscleen_US
dc.subjectMuscle Biochemistryen_US
dc.subjectMuscle Typesen_US
dc.subjectMusculoskeletal Anatomyen_US
dc.subjectWomen's Healthen_US
dc.subjectOsteopenia and Osteoporosisen_US
dc.titleThe Early Stage Adjacent Disc Degeneration after Percutaneous Vertebroplasty and Kyphoplasty in The Treatment of Osteoporotic VCFsen_US
dc.typeArticleen_US
dc.identifier.pmcidPMC3466231en_US
dc.contributor.corporatenameDepartment of Pathology-
dc.contributor.corporatenameCollege of Graduate Studies-
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