Adjuvant Chemotherapy for Patients with Stage III Colon Cancer: Results from a CDC-NPCR Patterns of Care Study.

Hdl Handle:
http://hdl.handle.net/10675.2/80
Title:
Adjuvant Chemotherapy for Patients with Stage III Colon Cancer: Results from a CDC-NPCR Patterns of Care Study.
Authors:
Cress, Rosemary D; Sabatino, Susan A; Wu, Xiao-Cheng; Schymura, Maria J; Rycroft, Randi; Stuckart, Erik; Fulton, John; Shen, Tiefu
Abstract:
OBJECTIVE: To evaluate adjuvant chemotherapy use for Stage III colon cancer. METHODS: This analysis included 973 patients with surgically treated stage III colon cancer. Socioeconomic information from the 2000 census was linked to patients' residential census tracts. Vital status through 12/31/02 was obtained from medical records and linkage to state vital statistics files and the National Death Index. RESULTS: Adjuvant chemotherapy was received by 67%. Treatment varied by state of residence, with Colorado, Rhode Island and New York residents more likely to receive chemotherapy than Louisiana residents. Older age, increasing comorbidities, divorced/widowed marital status, and residence in lower education areas or non-working class neighborhoods were associated with lower chemotherapy use. Survival varied by state but after adjustment for sex, sociodemographic and health factors, was significantly higher only for California and Rhode Island. Older age and lower educational attainment were associated with lower survival. Chemotherapy was protective for all comorbidity groups. CONCLUSION: Although adjuvant chemotherapy for Stage III colon cancer improves survival, some patients did not receive standard of care, demonstrating the need for cancer treatment surveillance. Interstate differences likely resulted from differences in local practice patterns, acceptance of treatment, and access.
Citation:
Clin Med Oncol. 2009 Nov 24; 3:107-119
Issue Date:
6-Aug-2010
URI:
http://hdl.handle.net/10675.2/80
PubMed ID:
20689617
PubMed Central ID:
PMC2872589
Type:
Journal Article
ISSN:
1177-9314
Appears in Collections:
Department of Health Informatics: Faculty Research and Presentations

Full metadata record

DC FieldValue Language
dc.contributor.authorCress, Rosemary Den_US
dc.contributor.authorSabatino, Susan Aen_US
dc.contributor.authorWu, Xiao-Chengen_US
dc.contributor.authorSchymura, Maria Jen_US
dc.contributor.authorRycroft, Randien_US
dc.contributor.authorStuckart, Eriken_US
dc.contributor.authorFulton, Johnen_US
dc.contributor.authorShen, Tiefuen_US
dc.date.accessioned2010-09-24T21:50:06Z-
dc.date.available2010-09-24T21:50:06Z-
dc.date.issued2010-08-06en_US
dc.identifier.citationClin Med Oncol. 2009 Nov 24; 3:107-119en_US
dc.identifier.issn1177-9314en_US
dc.identifier.pmid20689617en_US
dc.identifier.urihttp://hdl.handle.net/10675.2/80-
dc.description.abstractOBJECTIVE: To evaluate adjuvant chemotherapy use for Stage III colon cancer. METHODS: This analysis included 973 patients with surgically treated stage III colon cancer. Socioeconomic information from the 2000 census was linked to patients' residential census tracts. Vital status through 12/31/02 was obtained from medical records and linkage to state vital statistics files and the National Death Index. RESULTS: Adjuvant chemotherapy was received by 67%. Treatment varied by state of residence, with Colorado, Rhode Island and New York residents more likely to receive chemotherapy than Louisiana residents. Older age, increasing comorbidities, divorced/widowed marital status, and residence in lower education areas or non-working class neighborhoods were associated with lower chemotherapy use. Survival varied by state but after adjustment for sex, sociodemographic and health factors, was significantly higher only for California and Rhode Island. Older age and lower educational attainment were associated with lower survival. Chemotherapy was protective for all comorbidity groups. CONCLUSION: Although adjuvant chemotherapy for Stage III colon cancer improves survival, some patients did not receive standard of care, demonstrating the need for cancer treatment surveillance. Interstate differences likely resulted from differences in local practice patterns, acceptance of treatment, and access.en_US
dc.rightsThe PMC Open Access Subset is a relatively small part of the total collection of articles in PMC. Articles in the PMC Open Access Subset are still protected by copyright, but are made available under a Creative Commons or similar license that generally allows more liberal redistribution and reuse than a traditional copyrighted work. Please refer to the license statement in each article for specific terms of use. The license terms are not identical for all articles in this subset.en_US
dc.titleAdjuvant Chemotherapy for Patients with Stage III Colon Cancer: Results from a CDC-NPCR Patterns of Care Study.en_US
dc.typeJournal Articleen_US
dc.identifier.pmcidPMC2872589en_US
dc.contributor.corporatenameDepartment of Health Management and Informaticsen_US

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