Automated Reporter Quantification In Vivo: High-Throughput Screening Method for Reporter-Based Assays in Zebrafish

Hdl Handle:
http://hdl.handle.net/10675.2/775
Title:
Automated Reporter Quantification In Vivo: High-Throughput Screening Method for Reporter-Based Assays in Zebrafish
Authors:
Walker, Steven L.; Ariga, Junko; Mathias, Jonathan R.; Coothankandaswamy, Veena; Xie, Xiayang; Distel, Martin; Koster, Reinhard W.; Parsons, Michael J.; Bhalla, Kapil N.; Saxena, Meera T.; Mumm, Jeff S.
Abstract:
Reporter-based assays underlie many high-throughput screening (HTS) platforms, but most are limited to in vitro applications. Here, we report a simple whole-organism HTS method for quantifying changes in reporter intensity in individual zebrafish over time termed,
Citation:
PLoS One. 2012 Jan 4; 7(1):e29916
Issue Date:
4-Jan-2012
URI:
http://hdl.handle.net/10675.2/775
DOI:
10.1371/journal.pone.0029916
PubMed ID:
22238673
PubMed Central ID:
PMC3251595
Type:
Article
ISSN:
1932-6203
Appears in Collections:
Department of Cellular Biology and Anatomy: Faculty Research and Presentations

Full metadata record

DC FieldValue Language
dc.contributor.authorWalker, Steven L.en_US
dc.contributor.authorAriga, Junkoen_US
dc.contributor.authorMathias, Jonathan R.en_US
dc.contributor.authorCoothankandaswamy, Veenaen_US
dc.contributor.authorXie, Xiayangen_US
dc.contributor.authorDistel, Martinen_US
dc.contributor.authorKoster, Reinhard W.en_US
dc.contributor.authorParsons, Michael J.en_US
dc.contributor.authorBhalla, Kapil N.en_US
dc.contributor.authorSaxena, Meera T.en_US
dc.contributor.authorMumm, Jeff S.en_US
dc.date.accessioned2012-10-26T20:30:42Z-
dc.date.available2012-10-26T20:30:42Z-
dc.date.issued2012-01-4en_US
dc.identifier.citationPLoS One. 2012 Jan 4; 7(1):e29916en_US
dc.identifier.issn1932-6203en_US
dc.identifier.pmid22238673en_US
dc.identifier.doi10.1371/journal.pone.0029916en_US
dc.identifier.urihttp://hdl.handle.net/10675.2/775-
dc.description.abstractReporter-based assays underlie many high-throughput screening (HTS) platforms, but most are limited to in vitro applications. Here, we report a simple whole-organism HTS method for quantifying changes in reporter intensity in individual zebrafish over time termed,en_US
dc.rightsWalker et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_US
dc.subjectResearch Articleen_US
dc.subjectBiologyen_US
dc.subjectBiotechnologyen_US
dc.subjectGenetic Engineeringen_US
dc.subjectDevelopmental Biologyen_US
dc.subjectMorphogenesisen_US
dc.subjectOrganism Developmenten_US
dc.subjectStem Cellsen_US
dc.subjectGeneticsen_US
dc.subjectModel Organismsen_US
dc.subjectAnimal Modelsen_US
dc.subjectMolecular Cell Biologyen_US
dc.subjectSignal Transductionen_US
dc.subjectSignaling in Selected Disciplinesen_US
dc.subjectNeuroscienceen_US
dc.subjectSensory Systemsen_US
dc.titleAutomated Reporter Quantification In Vivo: High-Throughput Screening Method for Reporter-Based Assays in Zebrafishen_US
dc.typeArticleen_US
dc.identifier.pmcidPMC3251595en_US
dc.contributor.corporatenameDepartment of Cellular Biology and Anatomy-
dc.contributor.corporatenameGHSU Cancer Center-

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