Hdl Handle:
http://hdl.handle.net/10675.2/621526
Title:
Insulin-like Growth Factor-1 Receptor as a Prognostic Factor for Breast Cancer: A Systematic Review and Meta-Analysis
Authors:
Du, Helen; Koranteng, Patience; Stuart, Ansley ( 0000-0003-1154-0435 ) ; Sloan, Gloria; Weintraub, MJ; Cannon, Joseph
Abstract:
Breast cancer is the “malignant proliferation of epithelial cell lining the ducts or lobules of the breast” (1). Breast cancer is the most common form of cancer affecting women and the second leading cause of cancer death among women. Insulin-like growth factors are potent mitogens that have a role in cell proliferation, differentiation, and apoptosis. Overexpression of IGF-1R is thought to cause an increased risk in tumor metastasis and tumorigenesis. The aim of this project is to conduct a systematic review of IGF-1R expression in breast cancer and its relationship to patient survival. Our hypothesis is that increased insulin-like growth factor-1 receptor expression leads to poor prognosis in breast cancer patients.
Affiliation:
College of Allied Health Sciences - Clinical Laboratory Sciences
Issue Date:
10-Mar-2017
URI:
http://hdl.handle.net/10675.2/621526
Type:
Presentation
Language:
en_US
Appears in Collections:
Department of Medical Laboratory, Imaging & Radiologic Sciences: Student Research and Presentations

Full metadata record

DC FieldValue Language
dc.contributor.authorDu, Helenen
dc.contributor.authorKoranteng, Patienceen
dc.contributor.authorStuart, Ansleyen
dc.contributor.authorSloan, Gloriaen
dc.contributor.authorWeintraub, MJen
dc.contributor.authorCannon, Josephen
dc.date.accessioned2017-08-07T15:34:55Z-
dc.date.available2017-08-07T15:34:55Z-
dc.date.issued2017-03-10-
dc.identifier.urihttp://hdl.handle.net/10675.2/621526-
dc.description.abstractBreast cancer is the “malignant proliferation of epithelial cell lining the ducts or lobules of the breast” (1). Breast cancer is the most common form of cancer affecting women and the second leading cause of cancer death among women. Insulin-like growth factors are potent mitogens that have a role in cell proliferation, differentiation, and apoptosis. Overexpression of IGF-1R is thought to cause an increased risk in tumor metastasis and tumorigenesis. The aim of this project is to conduct a systematic review of IGF-1R expression in breast cancer and its relationship to patient survival. Our hypothesis is that increased insulin-like growth factor-1 receptor expression leads to poor prognosis in breast cancer patients.en
dc.language.isoen_USen
dc.subjectInsulin-like Growth Factoren
dc.subjectIGF-1 Receptoren
dc.subjectBreast Canceren
dc.subjectsystematic reviewen
dc.titleInsulin-like Growth Factor-1 Receptor as a Prognostic Factor for Breast Cancer: A Systematic Review and Meta-Analysisen_US
dc.typePresentationen
dc.contributor.departmentCollege of Allied Health Sciences - Clinical Laboratory Sciencesen
dc.description.advisorAnsley Stuart, Gloria Sloan, MJ Weintraub, Joseph Cannonen
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